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Dissecting the cellular and molecular mechanisms mediating neurofibromatosis type 1 related bone defects
Mouse model Osteoclasts Transforming growth factor-beta1
2015/5/21
Skeletal manifestations including short stature, osteoporosis, kyphoscoliosis, and tibial dysplasia cumulatively affect approximately 70% of patients with neurofibromatosis type 1 (NF1). Tibial pseuda...