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中国科学院动物研究所韩春生研究组关于小鼠精原干细胞体外减数分裂的文章在Stem Cell Reports发表(图)
中国科学院动物研究所 韩春生研究组 小鼠精原干细胞体外减数分裂 Stem Cell Reports
2016/7/6
不育症给个人、家庭和社会带来严重困扰。男性不育约占人类不育病例的50%,由多种遗传和表观遗传变异所致,主要表现为生殖细胞缺失以及减数分裂启动、完成和单倍体发育异常。长期以来由于缺少精原细胞干细胞的体外培养、基因修饰以及分化模型,人类对精子发生以及男性不育的机理研究进展缓慢。
Isolation and In vitro Culture of Pig Spermatogonial Stem Cell
Spermatogonial Stem Cell SSC Pluripotency Long Term Culture Pig
2016/4/29
The present study identified the favorable conditions for isolation, enrichment and in vitro culture of highly purified, undifferentiated pig spermatogonial stem cell (SSC) lines that proliferate for ...
Effects of Capsaicin on Adipogenic Differentiation in Bovine Bone Marrow Mesenchymal Stem Cell
Bovine Bone Marrow Mesenchymal Stem Cells [BMSCs] Capsaicin Adipogenesis Differentiation Apoptosis
2016/5/17
Capsaicin is a major constituent of hot chili peppers that influences lipid metabolism in animals. In this study, we explored the effects of capsaicin on adipogenic differentiation of bovine bone marr...
Generation of Embryonic Stem Cell-derived Transgenic Mice by Using Tetraploid Complementation
Human Resistin Tetraploid Embryonic Stem Cell Mouse
2016/4/18
The objective of this study was to generate transgenic mice expressing human resistin gene by using the tetraploid- embryonic stem (ES) cell complementation method. Human resistin gene was amplified f...