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【分析化学学术报告】Mass Spectrometric detection of membrane-bound proteins and their noncovalent interaction partners（图）
membrane-bound proteins noncovalent
2023/6/20
【分析化学学术报告】Mass Spectrometric detection of membrane-bound proteins and their noncovalent interaction partners
A new method for analyzing protein crystals – developed by Cornell researchers and given a funky two-part name – could open up applications for new drug discovery and other areas of biotechnology and ...
AI system can generate novel proteins that meet structural design targets（图）
AI系统 新型蛋白质 可调蛋白质
2023/6/6
MIT researchers are using artificial intelligence to design new proteins that go beyond those found in nature.
One of the major obstacles that those conducting research on carbohydrates are constantly working to overcome is the limited array of tools available to decipher the role of sugars. As a workaround, m...
One of the hallmarks of Alzheimer’s disease is the presence of neurofibrillary tangles in the brain. These tangles, made of tau proteins, impair neurons’ ability to function normally and can cause the...
Despite its minute size, a single cell contains billions of molecules that bustle around and bind to one another, carrying out vital functions. The human genome encodes about 20,000 proteins, most of ...
GhTULP34, a member of tubby-like proteins, interacts with GhSKP1A to negatively regulate plant osmotic stress
Tubby-like 蛋白基因 环境胁迫 棉花 组织发育
2024/5/17
Tubby-like蛋白基因(TULPs)以大型多基因家族的形式存在，在环境胁迫中发挥重要作用。然而，关于棉花中TULP家族基因的研究却知之甚少。本研究系统地对4种棉花TULPs的隶属关系、特征及其进化关系进行了鉴定和分析。转录组分析表明GhTULPs参与了环境胁迫和棉花组织发育。同时，我们还预测和分析了TULPs可能的分子调控机制和功能。GhTULP34作为候选基因，在盐胁迫下显著降低转基因拟南...
New programmable gene editing proteins found outside of CRISPR systems（图）
CRISPR系统 可编程基因 编辑蛋白 酶
2023/6/20
Within the last decade, scientists have adapted CRISPR systems from microbes into gene editing technology, a precise and programmable system for modifying DNA. Now, scientists at MIT’s McGovern Instit...
Proteins’ Fluorescence A Little Less Mysterious（图）
Proteins Fluorescence Little Less Mysterious
2018/2/1
Rice University scientists have effectively quenched a debate over the mechanism behind a fluorescent biosensor that monitors neurons by sensing changes in voltage.The work led by Rice theoretical che...
新乡学院生命科学技术学院基因工程课件 Expression and Modification of Recombinant Proteins
新乡学院生命科学技术学院 基因工程 课件 Expression and Modification of Recombinant Proteins
2017/7/17
新乡学院生命科学技术学院基因工程课件 Expression and Modification of Recombinant Proteins。
Cryo-EM images reveal how key biological machine unfolds problem proteins
Cryo-EM images biological machine proteins
2017/7/21
Hand over hand. That's how new, near-atomic resolution, 3-D snapshots show that a key biological machine unfolds a ribbon of protein through its central channel.The machine is a protein complex called...
Investigating folding stability and dynamics of proteins
folding stability dynamics proteins
2017/7/24
Hydrogels are polymer materials that can absorb a large amount of water, making them flexible like human tissue. They are used in a number of medical applications, including contact lenses, wound dres...
Ancient proteins may offer clues on how to engineer proteins that can withstand the high temperatures required in industrial applications, according to new research published in the Proceedings of the...
New computer model shows how proteins are controlled “at a distance”
New computer model shows proteins controlled at a distance
2017/3/14
Enzymes are large proteins that are involved in virtually every biological process, facilitating a multitude of biochemical reactions in our cells. Because of this, one of the biggest effort...
Scientists from Rice University, Baylor College of Medicine and other institutions are using synthetic biology to capture elusive, short-lived snippets of DNA that healthy cells produce on their way t...