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In Silico Target Prediction by Training Naive Bayesian Models on Chemogenomics Databases
Chemogenomics Databases Informatics
2015/5/26
The completion of Human Genome Project is seen as a gateway to the discovery of novel drug targets (Jacoby, Schuffenhauer, & Floersheim, 2003). How much of this information is actually translated into...
USE OF APRIORI KNOWLEDGE ON DYNAMIC BAYESIAN MODELS IN TIME-COURSE EXPRESSION DATA PREDICTION
DYNAMIC BAYESIAN NETWORKS HIDDEN MARKOV MODELS
2015/5/26
Bayesian networks, one of the most widely used techniques to understand or predict the future by making use of current or previous data, have gained credence over the last decade for their ability to ...
Researchers develop models to study polyelectrolytes, including DNA and RNA（图）
DNA RNA polyelectrolytes
2014/8/26
Researchers from North Carolina State University have developed a novel and versatile modeling strategy to simulate polyelectrolyte systems. The model has applications for creating new materials as we...
Use of murine models to test novel gene transfer strategies for the treatment of Fanconi anemia
Gene therapy mobilization hematopoiesis
2015/5/21
he dawn of the genetic era has allowed for investigation of gene transfer therapy as a treatment for certain diseases. Fanconi anemia (FA) is a rare genetic disorder in which the majority of patients ...