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2021年3月12日，中国科学院北京生命科学研究院赵方庆团队在Nature Biotechnology杂志上发表了题为“Comprehensive profiling of circular RNAs with nanopore sequencing and CIRI-long” 的文章，研究内容为高效测定环形RNA全长转录本的实验和计算方法。本研究主要是利用随机引物对环形RNA进行的滚环反转录扩...
RBRIdent: an algorithm for improved identification of RNA-binding residues in proteins from primary sequences
RNA-binding residues sequence-based prediction machine learning feature selection
2016/1/22
Rapid and correct identification of RNA-binding residues based on the protein primary sequences is of great importance. In most prevalent machine-learning-based identification methods; however, either...
FlexStem: Improving Predictions of RNA Secondary Structures With Pseudoknots by Reducing the Search Space
RNA Secondary Structures Pseudoknots
2010/12/17
RNA secondary structures with pseudoknots are often predicted by minimizing free energy, which is proved to be NP-hard. Due to kinetic reasons the real RNA secondary structure often has local instead ...
A Flexible Stem-Based Local Search Algorithm for Predicting RNA Secondary Structures Including Pseudoknots
Flexible Stem-Based Local Search Algorithm Predicting RNA Secondary Structures
2010/12/17
We demonstrate a new algorithm named FlexStem to predict RNA secondary structures with pseudoknots. Our approach is based on the free energy minimization criterion, and
utilizes a sophisticated energ...