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High doses of vitamin E in the treatment of disorders of the central nervous system in the aged
Aged elderly antioxidants
2016/6/1
Oxidative stress is a putative factor in the
pathogenesis of many human disorders of the central nervous
system. Therefore, antioxidants such as vitamin E have become
attractive as therapeutic agen...
Model for the regulation of energy balance and adiposity by the central nervous system
Body weight adipose tissue food intake
2016/5/30
In 1995, we described a new model for
adiposity regulation. Since then, data regarding the biology of
body weight regulation has accumulated at a remarkable rate and
has both modified and strengthe...
Central Nervous System Depressants Poisoning and Ventilator Associated Pneumonia: An Underrated Risk Factor at the Toxicological Intensive Care Unit
Intensive Care Unit Risk Factors Ventilator-Associated Pneumonia Toxicity
2016/1/26
Background: Ventilator-Associated Pneumonia (VAP) is the main cause of nosocomial infection at intensive care units (ICUs), which causes high mortality and morbidity.
Objectives: The objective of the...
Neuroprotective action of lithium in disorders of the central nervous system
Neuroprotective action lithium disorders central nervous system
2012/12/10
ObjectiveMethodsResultsConclusionSubstantial in vitro and in vivo evidence of neurotrophic and neuroprotective effects of lithium suggests that it may also have considerable potential for the treatmen...
Scientists discover gene that controls stem cells in central nervous system
Scientists gene stem cells central nervous system
2010/10/25
Scientists at the Medical Research Council (MRC) have discovered that a gene called Sox9 plays a critical role in how stem cells behave and is crucial in the development of the central nervous system....
Central nervous system reactions during heliox and trimix dives to 31 ATA
human trimix heliox Central nervous system
2009/7/16
Two groups of divers were compressed to 300 msw (984 fsw) with heliox (n = 3) and trimix (n = 3). Neuropsychological/neurological testing was performed repeatedly during the compression and on reachin...
Central nervous system reactions during heliox and trimix dives to 51 ATA, DEEP EX 81
nitrogen human heliox trimix
2009/7/15
Two groups of divers were compressed to 500 msw with heliox (n = 3) and trimix (n = 3). They were followed with repeated neuropsychological and neurological tests during compression, at stable interme...
Central nervous system oxygen toxicity in closed circuit scuba divers II
human oxygen toxicity Central nervous system
2009/7/14
Central nervous system oxygen toxicity is currently the limiting factor in underwater swimming/diving operations using closed-circuit oxygen equipment. A dive series was conducted at the Navy Experime...
Blood glucose as a predictive measure for central nervous system oxygen toxicity in conscious rats
hyperbaric oxygen toxicity rats Blood glucose
2009/7/14
Blood glucose concentration was measured during continuous electrocorticographic (ECoG) recording in conscious rats exposed to 3 and 5 atmosphere absolute oxygen (ATA O2). The preconvulsive oxygen-ind...
Central nervous system oxygen toxicity in the resting rat: postponement by intermittent oxygen exposure
pulmonary oxygen toxicity seizure hyperbaric outcomes nitrox
2009/7/14
Intermittent O2 breathing is a proven means of delaying pulmonary O2 toxicity during exposure to hyperbaric oxygen. The effect of an intermittent exposure in the pressure range toxic to the CNS was st...
Central nervous system decompression sickness:latency of 1070 human cases
decompression sickness neurological hyperbaric human spinal cord
2009/7/10
Many aspects of central nervous system (CNS) decompression sickness (DCS) are poorly understood, including the temporal pattern of its presentation and the pathogenic mechanisms involved in the develo...
Amino Acid Neurotransmitter Levels in the Cerebral Cortex of Mice Receiving Imipenem/Cilastatin -Lack of Excitotoxicity in the Central Nervous System
Amino acid imipenem mice neurotoxicity
2009/7/2
Imipenem, a very potent carbapenem derivative beta-lactam antibiotic, has recently found a major place in the treatment of antibiotic-resistant nosocomial infections. However, a convulsive side effect...
Central nervous system oxygen toxicity during hyperbaric treatment of patients with carbon monoxide poisoning
carbon monoxide multiplace seizure hyperbaric oxygen toxicity
2009/6/8
Hyperbaric oxygen (HBO2) is associated with a recognized risk for clinical central nervous system (CNS) toxicity. The risk for oxygen convulsions during routine hyperbaric treatment of most routine co...
Effect of the anti-motion-sickness medication cinnarizine on central nervous system oxygen toxicity
oxygen toxicity animal rat motion sickness sea sickness
2009/6/8
Severe seasickness could pose a serious problem in diving, and anti-seasickness medication should therefore be prescribed for the seasickness-susceptible diver. Cinnarizine may be used as a medication...
Central nervous system oxygen toxicity during routine hyperbaric oxygen therapy
Aged human Hyperbaric Oxygenation Retrospective Studies
2009/6/4
Hyperbaric oxygen therapy is associated with a recognized risk for clinically apparent central nervous system (CNS) toxicity. The risk for oxygen-induced convulsions during routine hyperbaric treatmen...