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Expression and Purification of the Recombinant Cytochrome P450 CYP141 Protein of Mycobacterium Tuberculosis as a Diagnostic Tool and Vaccine Production
Gene Expression Cytochrome P450 Enzyme System Mycobacterium Tuberculosis
2015/11/6
Background: Tuberculosis (TB) is regarded as a health problem worldwide, particularly in developing countries. Mycobacterium tuberculosis (M. tuberculosis) is the cause of this disease. Approximately ...
Cloning of the Recombinant Cytochrome P450 Cyp141 Protein of Mycobacterium tuberculosis as a Diagnostic Target and Vaccine Candidate
Cloning Cytochrome Mycobacterium Tuberculosis Diagnostic
2015/10/15
Background: Tuberculosis has been announced as a global emergency by World Health Organization and the second infectious agent of mortality worldwide. The general policy in the development of new vacc...
Impact of cytochrome P450 2C19*2 polymorphism on the clinical cardiovascular events after stent implantation in patients receiving clopidogrel of a southern Tunisian region
Clopidogrel CYP2C19*2 Polymorphism MACE Stent Thrombus
2013/2/19
Introduction: The concept of clopidogrel resistance, first described in biology is being strengthened by recent data from clinical epidemiology. The cardiologists have been sensitized to this concept ...
Abnormal Morphology of Spermatozoa in Cytochrome P450 17-hydroxylase/17, 20-lyase（CYP17）Deficient Mice
Gene deletion steroidogenesis mitochondria architecture fertility
2008/12/24
Cytochrome P450 17-hydroxylase/17, 20-lyase (CYP17) is crucial for cortisol and sex steroid biosynthesis. In a previous study we examined CYP17 function by generating mice with a targeted CYP17 d...
The pharmacogenetics of cytochrome P450 enzymes in personalized medicine
Personalized medicine Pharmacogenetics Cytochrome P450 CYP Individualized medicine
2010/4/20
Personalized medicine is partially enabled by in vitro diagnostics including pharmacogenomic, proteomic and other functional testing such as therapeutic drug management and toxicological testing. This...
The Cytochrome P450 System: Helping to Teach its Importance in Drug Metabolism and Drug Interactions
Cytochrome P450 System Teach its Importance Drug Metabolism Drug Interactions
2016/3/10
Knowledge of the cytochrome P450 system is important for the pharmacist because this enzyme participates in a number of drug interactions which may affect therapeutic outcomes and cause drug-induced t...