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DHA-rich n–3 fatty acid supplementation decreases DNA methylation in blood leukocytes: the OmegAD study
fish oil DHA EPA DNA methylation LINE-1 Alzheimer disease
2018/11/20
Background: Dietary fish oils, rich in long-chain n–3 (ω-3) fatty acids (FAs) [e.g., docosahexaenoic acid (DHA, 22:6n–3) and eicosapentaenoic acid (EPA, 20:5n–3)], modulate inflammatory reactions thro...
Comparison of biodistribution of ¹¹¹In-Tropolone leukocytes and 125I-human nonspecific polyclonal IgG in normal and induced inflammation mice for detection of inflammation
Immunoscintigraphy Acid citrate dextrose (ACD) Hydroxy ethyl starch (HES) Immunoglobulin (Ig) Percent injected dose per gram tissue (%ID/g)
2009/12/25
Human nonspecific polyclonal IgG and granulocytes, which accumulate in inflammation foci, were radiolabeled with 125I and ¹¹¹In-Tropolone, respectively. Biodistribution of these two rad...
Bronchoalveolar polymorphonuclear leukocytes in pulmonary oxygen toxicity
pulmonary oxygen toxicity animal rat Hyperbaric Oxygen hyperoxia
2009/5/8
We evaluated the hypothesis that polymorphonuclear leukocytes (PMN) contribute to lethal pulmonary oxygen toxicity by determining PMN in bronchoalveolar lavage (BAL) vs. survival time in models of O2 ...
EXERCISE-INDUCED HEAT SHOCK PROTEIN（HSP70）RESPONSE IN HUMAN SKELETAL MUSCLE AND LEUKOCYTES
heat shock proteins HSP70(72) exercise heat adaptation oxidative stress
2009/4/2
Heat shock proteins (HSPs) represent a family of highly conserved stress proteins found in all organisms from bacteria to humans. There is also substantial evidence that induction of HSPs synthesis ...
Development of Normal Reference Values for Seminal Reactive Oxygen Species and Their Correlation With Leukocytes and Semen Parameters in a Fertile Population
Oxidative stress male infertility Endtz test spermatozoa standardization
2008/12/24
Although reactive oxygen species (ROSs) are clearly implicated in the pathogenesis of male infertility, few studies have attempted to define the basal levels of ROSs in fertile men. Levels of ROS...
Utility of the Nitroblue Tetrazolium Reduction Test for Assessment of Reactive Oxygen Species Production by Seminal Leukocytes and Spermatozoa
Male infertility oxidative stress
2008/12/19
The purpose of this study was to evaluate the ability of spermatozoa and leukocytes in semen to produce reactive oxygen species (ROS) by using nitroblue tetrazolium (NBT) staining and to examine t...
Single and repeated moderate consumption of native or dealcoholized red wine show different effects on antioxidant parameters in blood and DNA strand breaks in peripheral leukocytes in healthy volunteers: a randomized controlled trial [ISRCTN68505294]
antioxidant parameters blood DNA
2008/4/23
Red wine (RW) is rich in antioxidant polyphenols that might protect from oxidative stress related diseases, such as cardiovascular disease and cancer. Antioxidant effects after single ingestion of RW ...
Oxatomide modifies membrane fluidity of polymorphonuclear leukocytes from children with allergic asthma
bronchial asthma leukocyte membrane fluidity oxatomide
2010/11/25
Background: Plasma membrane fluidity of polymorphonuclear leukocytes (PMN) was investigated in 10 allergic asthmatic children before and after oxatomide treatment.
Methods: Membrane fluidity was stud...
Effects of docosahexaenoic acid–rich n−3 fatty acid supplementation on cytokine release from blood mononuclear leukocytes: the OmegAD study
PBMCs EPA
2016/12/30
Dietary fish or fish oil rich in n−3 fatty acids (n−3 FAs), eg, docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), ameliorate inflammatory reactions by various mechanisms. Whereas...
Both lipid and protein intakes stimulate increased generation of reactive oxygen species by polymorphonuclear leukocytes and mononuclear cells
Lipids proteins reactive oxygen species leukocytes lipid peroxidation aging thiobarbituric acid–reactive substances TBARS polymorphonuclear leukocytes mononuclear cells
2016/12/17
Background: It was recently shown that glucose challenge leads to increased generation of reactive oxygen species (ROS) by polymorphonuclear leukocytes (PMNs) and mononuclear cells (MNCs).Objecti...
a-Tocopherol supplementation decreases production of superoxide and cytokines by leukocytes ex vivo in both normolipidemic and hypertriglyceridemic individuals
a-Tocopherol superoxide chemiluminescence, cytokines oxidized LDL hypertriglyceridemia men reactive oxygen species antioxidant
2016/6/3
Background: a-Tocopherol plays an important role in protecting
LDL against oxidation. However, additional effects of a-tocopherol
at the intracellular level may contribute to the clinical outcome
o...