搜索结果: 1-15 共查到“医学 RANTES”相关记录15条 . 查询时间(0.156 秒)
分析慢性肾脏病(chronic kidney disease,CKD)患者中成纤维细胞生长因子23(fibroblast growth factor 23,FGF23)水平与促炎性趋化因子之间的相关性。方法 选取神木市医院肾脏病科2017年1月~2019年1月收治的50例CKD Ⅱ~Ⅴ期患者和50例老年健康体检对照组纳入研究,分析受试对象血液和尿液中的生化指标。用ELISA技术测量FGF23水平,...
慢性鼻-鼻窦炎患者鼻息肉组织中CD69 RANTES的表达意义研究
慢性鼻-鼻窦炎 鼻息肉组织 CD69 RANTES
2020/12/23
探讨慢性鼻-鼻窦炎患者鼻息肉组织中CD69,RANTES的表达意义。方法:198名慢性鼻-鼻窦炎患者,分为不伴鼻息肉组92例,伴鼻息肉组106例;同时本院87名没有慢性鼻-鼻窦炎的健康志愿者作为一部分;测定各组CD69,RANTES mRNA,蛋白以及IL-4,IL-10,IL-12,IFN-γ,TNF-α,hs- CRP水平。
CCR5 on the NK Cells and its Ligand (RANTES) Expressions are Disrupted in South-Eastern Iranian Patients With Chronic Hepatitis B Infection
Chronic HBV Infection CCR5 RANTES NK Cells
2015/10/12
Background:: CCR5 is a receptor for CCL3 (MIP-1 α), CCL4 (MIP-1 α) and CCL5 (regulated on activation normal T cell expressed and secreted (RANTES)) and play important roles in recruitment of NK cells ...
观察不同糖浓度培养人肝癌细胞株HepG2和鼠源性细胞株H22趋化因子CCL5 mRNA表达水平,比较H22细胞株在糖尿病鼠和正常小鼠中的成瘤能力,探索CCL5在糖尿病合并肝癌中的作用机制。方法 不同糖浓度培养液(5.5、25 mmol/L)体外培养人肝癌HepG2细胞和鼠源性肝癌H22细胞,细胞划痕实验测定细胞的迁移能力;提取不同糖浓度培养HepG2和H22细胞的总RNA,RT-PCR法检测细胞中...
应用血清RANTES诊断严重脓毒症及预后判断的价值评价
脓毒症 趋化因子CCL5 诊断 预后
2014/7/16
检测严重脓毒症患者血清中受激活调节正常T细胞表达和分泌因子(RANTES)水平,并评价其对严重脓毒症的诊断和预后价值。方法 选取严重脓毒症患者40例为严重脓毒症组(SS组),同期门诊体检者20例为对照组,收集临床及实验室参数,计算APACHEⅡ评分和DIC评分,采用酶联免疫吸附测定(ELISA)方法检测血清RANTES的水平。结果 SS组患者血清RANTES水平[(3 175.91±1 341.7...
阿维A对寻常型银屑病患者趋化因子RANTES和MCP-1的影响
阿维A 银屑病 趋化因子CCL5 趋化因子CCL2
2012/3/27
观察阿维A对寻常型银屑病患者血清中和外周血单一核细胞(PBMC)内RANTES和MCP-1表达水平的影响。方法 分离并提取30例健康对照者及48例阿维A治疗前、后银屑病患者的血清及PBMC,血清采用ELISA检测其中RANTES和MCP-1的分泌水平,PBMC接受实时荧光定量PCR法检测细胞内RANTES和MCP-1的mRNA的水平,并进行临床PASI评分。结果 经ELISA检测发现,寻常型银屑病...
RANTES与糖尿病及其血管并发症
RANTES 糖尿病
2012/2/15
近来认为炎症因子和糖尿病及其并发症的发生发展密切相关。其中,C唱C 亚族趋化因子的作用日益受到关注。调节激活正常T 细胞表达和分泌的细胞趋化因子(regulate up唱on activation normal T cell expressed and secreted ,RANTES)属趋化性细胞因子C唱C 亚族家族成员,本文就其与糖尿病及其血管并发症的关系做一综述。
大鼠小肠移植排斥反应期移植肠RANTES表达的变化
大鼠 小肠移植排斥反应期 移植肠 RANTES表达
2009/7/28
目的: 探讨移植肠RANTES (regulated upon activation,normal T cell expressed and secreted 活化T细胞调节的,正常T细胞表达和分泌的因子)的表达在小肠移植急性排斥反应中的意义,以及他克莫司(FK506)对他的影响.方法: 选用成年健康♂SD和Wistar大鼠进行全小肠异位移植.实验分4组,第1组: 非手术对照组(Wistar); ...
Peripheral Blood Lymphocyte Activation and RANTES Levels in Asthma
Asthma lymphocyte activation RANTES
2009/6/16
Aim: Bronchial mucosal inflammation is one of the major characteristics of atopic asthma. Th2 activation and the related cytokine profile, eosinophil activation and infiltration play the main role in ...
RANTES在肝肾联合移植排斥反应中的表达及意义
RANTES 肝肾联合移植 排斥
2009/2/10
目的: 探讨大鼠肝肾联合移植排斥反应中移植物RANTES的表达. 方法: 将SD、Wistar大鼠随机分为正常对照组(A组)、同种同基因移植组(B组)、同种异基因移植组(C组). 应用袖套法建立大鼠肝肾联合移植模型. 分别对A组肝肾组织及移植后1、4、7 d肝肾组织进行活检, 行免疫组化染色, 然后进行图像半定量分析, 以检测正常及移植肝肾组织中RANTES的表达水平. 结果: 移植1、4、7 d...
一种新型重组免疫毒素DT390-Rantes真核表达质粒的构建及功能
2007/7/25
免疫毒素(IT)是一类将生物毒素与导向载体(抗体或细胞因子)连接起来构成的杂合分子,具有特定杀伤某些细胞的能力。随着T细胞的活化,在细胞表面会有许多膜受体表达,现已证实Rantes受体的表达仅限于活化的Th1细胞,而Th2细胞则没有表达,且这种膜受体的表达是稳定和持续的[1][2],因此,Rantes受体不仅可以作为识别Th1细胞和Th2细胞的标志,也为相关的免疫治疗提供了一个理想的靶位。本研究以...
IL-10 and RANTES are Elevated in Nasopharyngeal Secretions of Children with Respiratory Syncytial Virus Infection
Asthma interleukin-10 RANTES respiratory syncytial virus wheeze
2010/11/18
Of the subjects, 70 children were RSV positive and 40 were negative. Only 4 children were given a diagnosis of asthma by the pediatrician when NPAs were collected. The levels of IL-4, IL-10, and RANTE...
RANTES Production from Mononuclear Cells in Response to the Specific Allergen in Asthma Patients
asthma chemokine eosinophil mononuclear cells platelets RANTES
2010/11/19
Background: Eosinophils are considered to be the major inflammatory cells in asthma. Since regulated on activation, normal T expressed and secreted (RANTES) is a potent chemoattractant for various imp...
Inhalant corticosteroids inhibit mechanical strain-induced RANTES and eotaxin production by human airway smooth muscle cells
airway smooth muscle cells eotaxin inhaled corticosteroids mechanical strain RANTES
2010/11/24
The results showed that: (i) mechanical strain, including stretch and compression, stimulated ASM cells to produce RANTES and eotaxin; and (ii) FP and BUD inhibited mechanical strain-induced and TNF-α...
Lack of Association between Atopic Dermatitis and -401A/G Polymorphism in the Promoter Region of the RANTES Gene in Japanese
atopic dermatitis IgE polymorphism RANTES
2010/11/22
Background: Regulated on activation, normal T expressed and secreted (RANTES) has been known to be deeply involved in the pathophysiology of atopic dermatitis (AD). To examine whether a -401A/G polymo...