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Anti-IgE Antibody Therapy for Japanese Cedar Pollinosis: Omalizumab Update
anti-IgE therapy asthma immunotherapy omalizumab seasonal allergic rhinitis
2010/11/17
Seasonal allergic rhinitis (SAR) induced by Japanese cedar pollens is a substantial problem in Japan. Omalizumab, a novel humanized monoclonal anti-immunoglobulin E (IgE) antibody, has already been pr...
Recombinant soluble form of the high-affinity IgE receptor α subunit and anti-IgE antibody inhibit IgE synthesis by IgE-expressing B cells through distinct pathways
apoptosis divalent recognition IgE-binding agents IgE-expressing B cells interleukin-6 monovalent recognition
2010/11/24
Background: Both a recombinant soluble form of the high-affinity IgE receptor α subunit (rsFcεRIα) and anti-IgE antibody have been shown to be involved in the regulation of IgE synthesis. However, the...