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Rac GTPase isoform-specific regulation of NADPH oxidase and chemotaxis in murine neutrophils in vivo: Role of the C-terminal polybasic domain
Rac GTPase NADPH oxidase
2014/12/12
The Rho family GTPase Rac acts as a molecular switch for signal transduction to regulate various cellular functions. Mice deficient in the hematopoietic-specific Rac2 isoform exhibit agonist-specific ...
Chemotaxis is defined as the unidirectional movement of a cell in response to a chemical gradient in the direction from a low to a high concentration of chemoattractant.
Effect of Hot Water Extract from Agaricus Blazei Murill on Chemotaxis of Neutrophils
Neutrophil Chemotactic Activity Phagocytic Activity
2013/1/29
Hot water extract from the edible Brazilian mushroom, Agaricus Blazei Murill (ABM), is used for both traditional and alternative medicine. ABM is reported to stimulate anti-tumor, anti-infection, and ...
Neutrophil chemotaxis in acutely infected and clinically stable cystic fibrosis patients
Cystic fibrosis neutrophils chemotaxis
2009/7/1
Brochopulmonary infection in cystic fibrosis (CF) patients is associated with chronic progressive lung disease. The role of host factors, such as neutrophil functions, in the progressive pathologic pr...
A possible role of phospholipase C and phospholipase D in chemotaxis
10T1/2 Chemotaxis Phospholipase Neutrophil
2008/4/19
Cell chemotaxis plays a role in many cellular or individual actions suited to accomplishing a variety of purposes. These actions include activities of bacteria and Protista, cellular slime molds' migr...
Mechanisms involved in human eosinophil chemotaxis induced by the newly cloned C-C chemokine eotaxin
calcium chemotaxis eosinophil eotaxin signaling
2010/11/29
The present study was performed in order to investigate the mechanism(s) involved in eotaxin-induced normal human eosinophil chemotaxis using a 48-well microchemotaxis chamber assay. Eotaxin, at a wid...