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Gaskins et al. study reports on a new opportunity for breast cancer prevention
gut microbiome research beneficial gut microbiota epidemiologic study
2018/11/16
Gaskins et al. (1) reports on a promising new opportunity for gut microbiome research. Dietary manipulations to promote the growth of beneficial gut microbiota are currently being investigated as a no...
Lancet Oncology: 阿法替尼联合长春瑞滨与曲妥珠单抗联合长春瑞滨用于既往接受过一个曲妥珠单抗方案治疗后进展的HER2过度表达转移性乳腺癌的对比研究(LUX-Breast 1)：一项开放标签、随机3期临床试验
阿法替尼；长春瑞滨；曲妥珠单抗
2022/3/8
2016年1月25日，著名国际肿瘤学期刊Lancet Oncology(IF 24.69)在线发表了我院内科徐兵河教授作为通讯作者的一项国际多中心临床研究结果，同时配发了著名乳腺癌专家，美国Dana-Farber肿瘤研究所Krop教授的评论。该研究比较了HER2阳性乳腺癌患者在辅助或一线曲妥珠单抗治疗进展后，阿法替尼+长春瑞滨与曲妥珠单抗+长春瑞滨的效果。结果显示，接受阿法替尼治疗患者的无进展生存...
Overexpression of HER2/neu as a Prognostic Value in Iranian Women With Early Stage Breast Cancer;A Single Institute Study
Breast Neoplasms Oncogenes Biological Markers
2015/10/15
Background: Patients with early stage breast cancer with same treatment strategy can have markedly different outcomes. Human epidermal growth factor receptor 2 (HER2/nue) gene amplification or the sub...
Survival Rate of Breast Cancer Based on Geographical Variation in Iran, a National Study
Breast Neoplasm Survival Rate Pathologic Type Place of Residence Iran
2015/9/28
Background: Breast cancer is the most common cancer among women worldwide. Based on the latest Iranian national cancer department report, the total number of women registered with breast cancer was 69...
Aberrant methylation of Glutathione Stransferase P1 and E-cadherin in invasive ductal breast carcinoma and fibroadenoma
E-cadherin Breast invasive ductal carcinoma Fibroadenoma
2012/7/13
Objective To investigate the hypermethylation status of glutathione transferase P1(GSTP1) and E-cadherin (ECAD), TSGs (tumor suppressor genes) in our breast cancer samples and explore their correlatio...
The p21activated kinase 1 (PAK1) belongs to PAKs family, a group of highly evolutionarily conserved protein family of serine/threonine kinases, which acts as a downstream effector of the small GTPase...
2010年NCCN肿瘤学临床实践指南中《降低乳腺癌患病风险》（下面简称《指南》）已经公布。与往年相比，有些推荐内容有所更新，并且专家共识更加具体和重视循证医学的证据。