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Oral bioavailability and intestinal disposition of dehydroandrographolide in rats
脱水穿心莲内酯 药代动力学 肠道处置 Caco-2细胞 大鼠在体肠灌流
2012/8/20
目的研究脱水穿心莲内酯在大鼠体内的口服生物利用度和肠道处置，为其在临床的使用和开发提供有用的信息。方法研究脱水穿心莲内酯在大鼠体内的药代动力学行为。采用Caco-2细胞模型和大鼠在体肠灌流模型研究脱水穿心莲内酯在大鼠体内的肠道处置。结果脱水穿心莲内酯的口服绝对生物利用度是11.92%。在Caco-2细胞模型中，脱水穿心莲内酯从基底膜到顶端膜方向转运的表观渗透系数（5.37×10-5 cm/s）约等...
ANALYSIS OF CONTRASTING EFFECTS OF ALLOXAN AND MAGNESIUM ON PLASMA FREE FATTY ACIDS (FFA) IN DIABETES INDUCED RATS
Magnesium Free Fatty Acids DIABETES
2009/12/31
Background: Alloxan is on of the xenobiotic agents which is classified as diabetogenic materials. Magnesium is an important cofactor regulating the activity of carbohydrate enzymes and lipid synthesis...
Hypolipidemic effects of alcoholic extract of eucalyptus (Eucalyptus globulus Labill.) leaves on diabetic and non-diabetic rats
Eucalyptus (Eucalyptus globulus Labill) Lipids diabetes
2009/11/26
Background: In traditional medicine, leaves of eucalyptus (Eucalyptus globulus Labill.) possess interesting biological properties such as antioxidant, antibacterial and antiviral effects. The aim of t...
The Effect of Diclofenac Sodium on the Renal Parenchyma During Complete Unilateral Ureteral Obstruction of the Rats
Ureteral obstruction hydronephrosis diclofenac cefoperazone
2009/7/2
An experimental study was designed to investigate the effect of diclofenac sodium (DS) on both renal parenchyma during complete unilateral ureteral obstruction. In 40 adult rats, left ureteropelvic ju...
The Evaluation of Microanastomoses in Rats with Color Doppler Ultrasonography
Color Doppler Ultrasonography Microanastomosis Vascular patency
2009/7/2
Purpose: To evaluate the vascular patency of microanastomoses in rats with color Doppler ultrasonography. Materials and Methods: 15 superficial femoral and 15 carotid arterial end-to-end anastomoses w...
Effects of ACE Inhibition and AT1 Receptor Blockade on Cardiac Ischaemia-Reperfusion Induced Mortality and Cardiac Markers in Rats
Myocardial Ischemia-Reperfusion Arrhythima Cardiac Marker Troponin Captopril Losartan
2009/6/22
Many studies have established the therapeutic benefits of angiotensin-converting enzyme (ACE) inhibitors such as reducing reperfusion arrhythmias, and angiotensin II type 1 (AT1) blocker may have simi...
The Effect of Caffeic Acid Phenethyl Ester (CAPE) Treatment on Levels of MDA,NO and Antioxidant Enzyme Activities in Retinas of Streptozotocin-Induced Diabetic Rats
Antioxidant enzymes caffeic acid phenethyl ester diabetic retinopathy lipid peroxidation
2009/6/16
Aim: This study was performed to determine the effect of caffeic acid phenethyl ester (CAPE) treatment on levels of malondialdehyde (MDA) and nitric oxide (NO) and activities of antioxidant enzymes in...
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书名
Cell proliferation in ependymal/subventricular zone and nNOS expression following focal cerebral ischemia in adult rats
语种
英文
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作者
Pengbo Zhang,Yong Liu,Jie Li,Qianyan Kang,Yingfang Tian,X...
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书名
Vascular Endothelial Growth Factor Gene Therapy Enhances Survival of Ischemic Random Skin Flaps in the Rats
语种
英文
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作者
杨立文,张吉翔
第一作者单位
出版社
《British Journal of Plastic Surgery》in press
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出...
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Effect of drugs on mRNA expression of voltage-gated potassium channels myocardial remodeling by charonic L-thyroxine adminstration in rats
语种
英文
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撰写
作者
Fang-Zhi Fang,Zi-Zhen Wang,De-Zai D...