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Staphylococcus aureus colonization in contact hypersensitivity induces a shift in cutaneous cytokine milieu from a Th1- to a Th2-type profile
atopic dermatitis Staphylococcus aureus Th1 cells Th2 cells
2010/11/24
In TNCB-challenged lesions inoculated with S. aureus, the levels of IL-2 mRNA decreased; in contrast, mRNA levels of IL-4 and IL-5 were upregulated. In mite antigen-challenged lesions, IL-4 and IL-5 m...
Transient shift toward T helper 1 cytokine production by peripheral blood mononuclear cells following successful treatment of patients with atopic dermatitis
atopic dermatitis cytokines interferon-γ interleukin-10 interleukin-12 peripheral blood mono-nuclear cells response to treatment
2010/11/24
Interferon-γ and interleukin (IL)-12 pro-duction increased significantly after 2 weeks treatment (P < 0.005 and P < 0.05, respectively), while IL-10 production decreased significantly after 2 and 4 we...