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The automated analysis of rat sperm motility following subchronic epichlorohydrin administration：methodologic and statistical considerations
rat sperm motility subchronic epichlorohydrin administration methodologic and statistical considerations
2009/2/23
The automated analysis of sperm motion endpoints is potentially useful in identifying male reproductive toxicants and ultimately in predicting fertility in humans. The present study was designed to ...
The regulation of the proliferation and differentiation of rat Leydig cell precursor cells after EDS administration or daily HCG treatment
Leydig cell Leydig cell precursor LH hCG EDS proliferation
2009/2/23
The proliferation and differentiation of possible Leydig cell precursors in adult rats were studied after destruction of the existing Leydig cells with EDS or after daily treatment with hCG. After 2...
The effect of long-term opiate antagonist administration to pubertal boys
Puberty opiate control of gonadotropins
2009/2/23
To test further the hypothesis that opiatergic pathways controlling gonadotropin production may be functional during early to mid adolescence, nine pubertal boys with bone ages ranging from 10 to 15...
Reversibility of long-term effects of GnRH agonist administration on testicular histology and sperm production in the nonhuman primate
GnRH agonist LH testosterone testis morphology electron microscopy monkeys
2009/2/23
The present investigation evaluates the long-term effects of GnRH agonist treatment on testicular histology, sperm production and the subsequent recovery of these parameters. Four adult rhesus monke...
Effects of neonatal estrogen administration on rat testis development with particular reference to Sertoli cells
neonatal estrogen administration rat testis development Sertoli cells
2009/2/23
An ultrastructural and morphometric study of the testes in 15-, 22-, 45-, and 90-day-old neonatally estrogenized rats was performed. At 45 days of age, the Sertoli cells appeared immature in estroge...
Administration of constant low doses of androgens to steers by silastic implant. Suppression of gonadotropins and peripheral conversion of androgens
androgen implants steers gonadotropins peripheral metabolism of androgens
2009/2/20
Yearling Hereford calves approximately 300 kg in weight were castrated and assigned to one of six treatment groups receiving subcutaneous implants (3 implants, 0.5 cm diameter by 10 cm length, 10% s...
Inability of continuous long-term administration of D-Nal（2）6-LHRH to abolish fertility in male rats
D-Nal(2)6-LHRH fertility male rats
2009/2/19
A highly potent agonist of LHRH, [6-D-(2-naphthyl)-alanine]-LHRH, was administered chronically for 12 weeks to adult male rats by repetitive implantation of pellets, and its effects upon mating, fer...
The effect of estrogen administration in vivo on the elemental composition of the intraluminal fluids of the seminiferous tubules, rete testis, and epididymis of the rat
epididymis spermatozoa estrogen elements
2009/2/19
The maturation of spermatozoa in the epididymis is dependent upon the presence of androgens. This study examined the effects of androgen suppression by estradiol valerate on the elemental compositio...
The Effect of Acute and Chronic Ethanol Administration on Prolactin Secretion in Male Rats
ethanol prolactin glutamate decarboxylase
2009/2/19
The effect of acute and chronic administration of ethanol on prolactin secretion in male rats was investigated under basal conditions and after the administration of sulpiride. The effect of ethan...
Impact of Pulsatile Administration of Gonadotropin-Releasing Hormone on the Pituitary-Testicular Axis of the Immature Rat
pulsatile gonadotropin-releasing hormone administration luteinizing hormone androgens
2009/2/19
Effects of administering low doses of GnRH (30 ng/100 g body weight) at various frequencies on the pituitary-testicular axis were investigated. During a 6-hour treatment period, GnRH was administe...
Further Studies on the Inhibitory Effect of [D-A1a6, des-Gly-NH210]LHRH Ethylamide on Spermatogenesis and Steroidogenesis in the Rat：Reversibility and Effect of Androgen Administration
antifertility spermatogenesis LHRH agonist
2009/2/18
Following the recent observation that chronic treatment with [D-Ala6, des-Gly-NH210]LHRH ethylamide, a potent LHRH agonist, leads to an almost complete degeneration of seminiferous tubules in the ra...
Gonadal and pituitary responsiveness of stallions is not down-regulated by prolonged pulsatile administration of GnRH
Equine hypothalamic-pituitary-gonadal axis ref ractoriness
2009/2/17
The objective of this study was to determine if prolonged pulsatile administration of homologous gonadotropin-releasing hormone (GnRH) at therapeutic or 5x therapeutic doses would cause down-regul...
Suppressive effects of chronic hyperprolactinemia on penile erection and yawning following administration of apomorphine to pituitary-transplanted rats
Prolactin testosterone pituitary transplantation castration
2009/2/17
Recent studies showed in vivo and in vitro that acutely introduced prolactin (PRL) excess was capable of diminishing penile erectile function independently of the LH-testosterone (T) dynamics. In th...
Deformation of the rat Sertoli cell by oral administration of carbendazim（methyl 2-benzimidazole carbamate）
Carbendazim displacement microtubules Sertoli cell
2009/2/13
Carbendazim (methyl 2-benzimidazole carbamate; MBC) has been reported to disrupt the microtubules of Sertoli cells in the rat, suggesting that the cells exposed to carbendazim would fail to maintain...
Intratesticular testosterone concentration following intratunical administration in the hypogonadal animal
Testosterone tunica vaginalis hypogonadism infertility
2009/2/13
The serum and intratesticular testosterone concentration (ITC) after testosterone administration in the tunica vaginalis (TV) sac compared to parenteral administration was studied in 20 dogs that were...