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A simple, clinical assay to evaluate the acrosin activity of human spermatozoa
acrosin activity human spermatozoa
2009/2/23
Acrosin, a sperm-specific acrosomal proteinase, has an essential role in the fertilization process. Low levels of acrosin appear to be associated with subfertility and infertility, and the acrosin a...
Clinical experience with an artificial spermatocele
Clinical experience artificial spermatocele
2009/2/20
Artificial spermatoceles were implanted into three patients with congenital absence of the vas. In each case, the testicular biopsy demonstrated normal spermatogenesis, and the dilated epididymal ...
Clinical studies in an adult male patient with “isolated follicle stimulating hormone （FSH）deficiency”
isolated FSH deficiency gonadotropin deficiency hypogonadism infertility FSH deficiency
2009/2/20
Previous reports concerning isolated follicle stimulating hormone (FSH) deficiency and its possible pathogenesis have been conflicting. Both "normal" and "abnormal" FSH response to luteinizing hormone...
Human sperm penetration in bovine cervical mucus. Clinical studies I
Human sperm penetration bovine cervical mucus
2009/2/19
Penetration of spermatozoa in bovine cervical mucus (BCM) from two groups of men was investigated and correlated with the different parameters of spermograms from these same subjects. Sperm penetr...
Guidelines for the Clinical Testing of Male Contraceptive Drugs
Guidelines Clinical Testing Male Contraceptive Drugs
2009/2/19
The development of male contraceptive drugs is of great scientific importance for andrologists as well as being of vital world interest. The American Society of Andrology, therefore, welcomed the op...
A pilot study demonstrating clinical benefit from intralesional interferon alpha 2B in the treatment of Peyronie's disease
Nonsurgical therapy intralesional IFN-a-2B
2009/2/18
Intralesional therapy is a less invasive method for the treatment of Peyronie's disease. The objective of this study was to evaluate intralesional injections of interferon alpha 2B (IFN-alpha-2B) ...
Changes in the endocrinological milieu after clomiphene citrate treatment for oligozoospermia：the clinical significance of the estradiol/testosterone ratio as a prognostic value
E5/T ratio clomiphene citrate male infertility
2009/2/12
We have already reported that the rate of increase in the estradiol/testosterone ratio (E2/T ratio) following human chorionic gonadotropin (hCG) injection has prognostic value in the treatment of olig...
Human sperm acrosin. Further studies with the clinical assay and activity in a group of presumably fertile men
spermatozoa acrosin Triton X-100 fertility
2009/2/11
The goals of this study were to determine the effect of the nonionic detergent, Triton X-100, on the recovery of acrosin in the clinical assay (Kennedy et al, 1989), since previous investigations ...
Is the randomized clinical trial the gold standard of research?
randomized clinical trial gold standard of research
2008/12/29
All research has flaws. Some flaws are so trivial that the research can still stand as the definitive study. Other flaws prevent a study from being definitive, but the study still provides useful gu...
Evaluation of a container for collection and shipment of semen with potential uses in population-based, clinical, and occupational settings
Evaluation container collection and shipment of semen population-based clinical occupational settings
2008/12/25
Large, population-based studies of semen quality are encumbered by the logistics and expense of obtaining semen samples from men who live in a variety of locations. A prototype semen collection and ...
Clinical Use of Pentoxifylline for Activation of Immotile Testicular Sperm Before ICSI in Patients With Azoospermia
Testicular biopsy human spermatozoa phosphodiesterase inhibitors motility stimulants fertilization
2008/12/23
The testicular sperm from biopsy and frozen/thawed tissue are frequently immotile. The purpose of our retrospective study was to assess the effect of short exposure of testicular samples with only i...
Vasectomy Reversal in the Presence of Diminished Ovarian Reserve：A Complex Clinical Conundrum
Vasectomy Reversal Diminished Ovarian Reserve Clinical Conundrum
2008/12/23
Clinical reproductive practice is often multivariate: multiple conditions in the male and/or female may coexist to confound diagnoses and therapeutic strategies. Given that treatment of an underlyin...
Clinical Male Infertility and Assisted Reproduction
Clinical Male Infertility Assisted Reproduction
2008/12/23
The current issue of Journal of Andrology is designated as a Special Issue on Clinical Male Infertility and Assisted Reproduction. The opportunity to create a Special Issue developed because of a ...
Oral Pharmacotherapy for Male Sexual Dysfunction：A Guide to Clinical Management
Oral Pharmacotherapy Male Sexual Dysfunction Clinical Management
2008/12/23
Scope of Book: An extremely comprehensive review of male sexual dysfunction as it relates to the practicing clinician, with some additional topics thrown in as well (eg, female sexual dysfunction). ...
Preservation of Testicular Arteries During Subinguinal Microsurgical Varicocelectomy: Clinical Considerations
Varicocele male infertility semen
2008/12/22
Microsurgical varicocelectomy with intentional preservation of the testicular artery(ies) is regarded as the gold standard approach to varicocele repair. We sought to determine whether the number of...