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Mass Spectrometric Approaches to Probing the Redox Function of Ape1
mass spectrometry Ape1 E3330 NEM Labeling
2015/5/25
Human apurinic/apyrimidinic endonuclease 1 (hApe1) is a multi-functional protein having two major functions: apurinic/apyrimidinic endonuclease activity for DNA damage repair and redox activity for ge...
Paclitaxel alters the function of the small diameter sensory neurons
Small diameter sensory neurons paclitaxel vasodilatation
2015/5/21
Although paclitaxel is a commonly used anti-neoplastic agent for the treatment of solid tumors, therapy often results in a number of side effects, the most debilitating of which is peripheral neuropat...
Hand2 function within non-cardiomyocytes regulates cardiac morphogenesis and performance
Notch Signaling EphrinB2 bHLH Transcription Factor
2015/5/21
The heart is a complex organ that is composed of numerous cell types, which must integrate their programs for proper specification, differentiation, and cardiac morphogenesis. During cardiac developme...
Function following limb salvage procedures for bone sarcoma
limb salvage procedures bone sarcoma
2015/4/1
Bone sarcomas are the fourth most common cancer in individuals under 25 years. Osteosarcoma is the most common form of sarcoma in this population, with distal femur the most common tumour location. Be...
Although it is generally accepted that renal function declines with increasing age, this should not be assumed in all cases. The estimation of renal function on an individual patient basis is therefor...
SPEECH AND SWALLOWING FUNCTION IN HEAD AND NECK CANCER PATIENTS: WHAT DO WE KNOW?
Head and neck cancer Head
2015/3/20
In this paper, we report on common speech and swallowing dysfunction that occurs after surgery, radiotherapy or
chemo-radiotherapy for head and neck cancer (oral cavity, pharynx and larynx sites). We...
Radioiodine Treatment Effects on Lacrimal Glands Function in Patients with Thyroid Cancer
Radioiodine Thyroid Cancer Lacrimal glands Iodine therapy Long acting effects
2010/1/5
Introduction: There is a limited number of case reports published in the past decade confirming the radio-iodine presence in the tear. These observations as well as reported cases of salivary and lacr...