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近日,宁波大学医学院金晓锋博士在肿瘤领域取得重大科研成果。金晓锋以第一作者在肿瘤领域国际顶级期刊《Leukemia》上发表题为《CRL3-SPOP Ubiquitin Ligase Complex Suppresses the Growth of Diffuse Large B-cell Lymphoma by Negatively Regulating the MyD88/NF-κB Signa...
肿瘤医院放射治疗科李晔雄教授领导的NK/T细胞淋巴瘤全国多中心协作组开展的结外鼻型NK/T细胞淋巴瘤列线图(Nomogram)研究日前在世界顶尖级肿瘤杂志《Leukemia》发表(2014年IF 10.43)。这一研究在国际上首次提出了结外鼻型NK/T细胞淋巴瘤的列线图模型,该模型可对治疗前患者进行疾病风险评分,并预估患者5年总生存率。该模型的建立可为后续基于风险分层的治疗决策提供依据。
Chronic myelogenous leukemia (CML) is a stem cell disorder sometimes associated with lymphoproliferative disorders. CML may precede a lymphoproliferative disorder. There are a few reports showing asso...
Given preliminary evidence of timed, sequential chemotherapy of high dose cytosine arabinoside the current study was initiated to assess the side effects and efficacy of this regimen in patients with ...
Background: Acute fulminant fungal sinusitis is a rapidly progressive disease with high mortality (50-80%) and occurring with increasing frequency in patients with acute leukemia. The purpose of the p...
Involvement of the testes - one of the most common sites of relapse in Acute Lymphoblastic Leukemia (ALL) - usually presents with painless enlargement of one or both testes. Testicular involvement occ...
Immunoglobulin heavy chain rearrangements provide a specific identity of complementarity determining region 3 (CDR3) DNA sequences. For this reason, CDR3 regions may be used in the diagnosis of malign...
Antisense oligodeoxynucleotides (AS-ODNs) are short DNA sequences synthesized complementary to the mRNA and they inhibit the expression of the target gene by forming a mRNA-DNA duplex. This strategy c...
Hepatomegaly and mild elevation of serum transaminase values that might be caused by infiltration of leukemic cells are seen in some cases of leukemia. It may result from such conditions as viral hep...
Treatment of acute myeloid leukemia (AML): Recent results and new directions。
Multi drug resistance(MDR) is a major problem in the treatment of cancer and hemalological malignancies. This resistance is multi factorial and is the result of decreased intra cellular drug accumulat...

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