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Hypoxia Inducible Factor-1α (HIF-1 α) and its Role in Tumour Progression to Malignancy
HIF HIF-1α Hypoxia Malignancy Cancer Cancer Therapy
2015/7/28
Hypoxia is a condition in which an area of the body or a tissue is deprived of sufficient supply of oxygen. The lack of nutrients in a hypoxic tissue generally causes apoptosis but some cells are able...
Intratumour heterogeneity in the progression to breast cancer metastasis
Intratumour heterogeneity breast cancer metastasis
2015/4/14
Unlike the great advances that have been made in reducing breast cancer mortality through the multidisciplinary treatment of primary disease, much less is understood about the natural history of metas...
NEURAL CORRELATES AND PROGRESSION OF SACCADE IMPAIRMENT IN PREMANIFEST AND MANIFEST HUNTINGTON DISEASE
MRI saccades Huntington disease
2015/5/21
Huntington disease (HD) is an autosomal dominant disorder characterized by progressive decline of motor, cognitive, and behavioral function. Saccades (rapid, gaze-shifting eye movements) are affected ...
Researchers at the Medical Research Council (MRC) have identified that a key protein called germinal center-associated nuclear protein (GANP) could shed light on how cancers of the immune system such ...