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CORRELATING IRINOTECAN AND CAPECITABINE TREATMENT FOR COLORECTAL CANCER TO GENE EXPRESSION, POLYMORPHISMS, AND CLINICAL OUTCOMES
Irinotecan CPT-11 Capecitabine
2015/5/25
Colorectal cancer is the third most common type of cancer and the third most common cause of cancer-related mortality. There are three types of treatment available to patients, either individually or ...
The use of gene expression profiling in tumour classification and management
gene expression profiling tumour classification management
2015/3/13
Microarray-based transcript profiling is a technique used to measure the steady-state levels of gene expression on a genome-wide scale in a cell or tissue. The technology essentially involves making a...
Efficacy of Recombinant Adenoviral Human p53 Gene in Treatment of Malignant Pleural or Peritoneal Effusions
p53 gene Gene therapy Malignant effusion Intra-cavity infusion
2013/12/4
Background and objective Once the malignant pleural or peritoneal effusion is developed it is difficult to control. This report presents a new method for controlling the malignant effusions.
Me...
CD4+ T cell mediated tumor immunity following transplantation of TRP-1 TCR gene modified hematopoietic stem cells
Melanocyte Differentiation Antigen Lentiviral Vectors
2015/5/21
Immunotherapy for cancer has held much promise as a potent modality of cancer treatment. The ability to selectively destroy diseased cells and leave healthy cells unharmed has been the goal of cancer ...
Gene Polymorphisms and Chemotherapy in Non-small Cell Lung Cancer
Lung neoplasms Genetic polymorphism Drug therapy
2013/12/10
The phamacogenetics is being used to predict whether the selected chemotherapy will be really effective and tolerable to the patient. Irinotecan, oxidized by CYP3A4 to produce inactive compounds, is u...
Nanoparticles target ovarian cancer--New gene therapy technique could fight late-stage tumors
ovarian cancer gene therapy technique late-stage tumors
2009/8/3
Tiny particles carrying a killer gene can effectively suppress ovarian tumor growth in mice, according to a team of researchers from MIT and the Lankenau Institute.The findings could lead to a new tre...
CANCER GENE THERAPY USING CYTOKINE AND CHEMOKINE GENES
Adenovirus CC chemokine granulocyte macrophage-colony stimulating factor interleukin-2 retrovirus secondary lymphoid tissue chemokine
2009/7/15
Surgical or radiotherapy-mediated eradication of tumors gives the best opportunity for cure, if the tumor is restricted to the primary sites. Chemotherapy is employed for disseminated disease but freq...
Use of RNA interference technology for cancer specific gene silencing
RNA interference siRNA cancer gene therapy
2009/7/15
RNA interference (RNAi) can be applied to human cancer cells by using small interfering RNAs (siRNAs) for inhibition of activated oncogenes' expression with the amelioration of several malignant pheno...
Gene Therapy in Human Breast Cancer
gene therapy breast cancer viral vectors vector targeting
2009/6/26
Gene therapy, being a novel treatment for many diseases, is readily applicable for the treatment of cancer patients. Breast cancer is the most common cancer among women. There are many clinical protoc...
One step closer to turning off cancer genes with gene-silencing
cancer genes gene-silencing one step
2009/6/5
Researchers at The University of Queensland have developed a way to deliver drugs which can specifically shut down cancer-causing genes in tumour cells while sparing normal healthy tissues.
Decoding Gene Expression in Cancer Tumors Using Non-Invasive Imaging
Cancer Tumors radiology
2007/5/31
May 21, 2007，By correlating images of cancerous liver tissue with gene expression patterns, a research team led by a radiologist at the University of California, San Diego (UCSD) School of Medicine ha...