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探讨新技术(Gene-Xpert MTB/RIF,简称为Xpert)在人类免疫缺陷病毒(HIV)合并结核分枝杆菌感染筛查中的临床应用,期望为HIV/TB的感染者找到快捷、准确的检测方法或者检测方法组合。方法 收集云南省传染病医院2017年3月至2018年12月收治的HIV住院患者278例痰液标本,每例患者痰液标本均用Xpert、罗氏培养法和直接涂片萋-纳抗酸染色法三种方法进行检测。
Interest has increased in understanding the interaction between genes and nutrients in the development of atherosclerosis (1). Many studies have addressed the role of such interactions in the respo...
Down syndrome, or trisomy 21, is a complex genetic disease resulting from the presence of 3 copies of chromosome 21. The origin of the extra chromosome is maternal in 95% of cases and is due to the...
One of the major advances in preventing malformations in the past few decades had its origin in the observation by Smithells et al (1) that multivitamin preparations are protective against neural t...
Two German sisters aged 14 and 17 y were admitted to the Tübingen eye hospital with a history of night blindness. In both siblings, plasma retinol binding protein (RBP) concentrations were below th...
Biesalski et al (1) present a novel case of 2 sisters aged 14 and 17 y with very low plasma retinol concentrations (0.19 mmol/L) and plasma concentrations of retinol binding protein (RBP) below the...
Vitamin D plays an important role in preserving healthy bones, and has additional roles in the body, including modulation of cell growth, differentiation, neuromuscular and immune function, and anti-i...
Background: The importance of sialic acid binding adhesin (sabA) as a new outer membrane protein in gastroduodenal diseases has been recognized. The prevalence rate of sabA gene varies in different ge...
Background: Ability of athletes in speed or endurance contests somehow is determined by inherited muscle fiber types. One of the important genes involved in sport genetics is ACTN3 that is located on ...
Background: The emergence and spread of chloroquine resistant Plasmodium falciparum in the world stimulated some investigators to consider different aspects of chloroquine resistance in human and rode...
Background: The emergence and spread of chloroquine resistant Plasmodium falciparum in the world stimulated some investigators to consider different aspects of chloroquine resistance in human and rode...
Background: Ghrelin is an endogenous peptide that stimulates growth hormone secretion, enhances appetite, and increases body weight and may play a role in eating disorders.Objective: The purpose was t...
Background: Despite adiponectin's presumed role in fatty acid oxidation and energy homeostasis, little is known about the effect of gene variants on substrate oxidation, energy expenditure, and adipos...
Background: Diets rich in whole-grain cereals and foods with a low glycemic index may protect against type 2 diabetes, but the underlying molecular mechanisms are unknown.Objective: The main objective...

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