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Microbial modulation of innate defense: goblet cells and the intestinal mucus layer
goblet cells mucins mucus
2016/6/14
The gastrointestinal epithelium is covered by a
protective mucus gel composed predominantly of mucin glycoproteins
that are synthesized and secreted by goblet cells.
Changes in goblet cell function...
Effect of plasma metabolites of (+)-catechin and quercetin on monocyte adhesion to human aortic endothelial cells
endothelial cell reactive oxygen species rats
2016/6/13
Flavonoids may exert their health benefit in cardiovascular
disease by modulating monocyte adhesion in the
inflammatory process of atherosclerosis. Most in vitro studies
used forms of flavonoids pr...
Chocolate procyanidins decrease the leukotriene-prostacyclin ratio in humans and human aortic endothelial cells
Chocolate eicosanoids flavonoids
2016/6/12
Polyphenolic phytochemicals inhibit vascular and
inflammatory processes that contribute to disease. These effects
are hypothesized to result from polyphenol-mediated alterations
in cellular eicosan...
Effect of trans fatty acids on calcium influx into human arterial endothelial cells
atherosclerosis umbilical cord magnesium
2016/6/1
A recent task force of The American Society for
Clinical Nutrition and American Society for Nutritional Sciences
recommended in a position paper on trans fatty acids that
models be developed to ass...
Carotenoids in human buccal mucosa cells after 4 wk of supplementation with tomato juice or lycopene supplements
Lycopene phytofluene carotenoids
2016/6/1
Lycopene has been identified as a phytochemical
with potentially protective health benefits.
Effects of high compared with low calcium intake on calcium absorption and incorporation of iron by red blood cells in small children
Calcium absorption iron absorption preschool children
2016/5/31
The potential benefits of increasing calcium
intake in small children must be balanced with the potential risk
to iron utilization from high calcium intakes.
Effects of Histone Deacetylase Inhibitors on Vitamin D Activity in Human Breast Cancer Cells
Sulforaphane histone deacetylase inhibitors vitamin D receptor
2014/11/7
Breast cancer is one of the leading causes of death in women cancer cases worldwide. Cancer is the result of environmental and genetic factors that contribute to alterations in cellular control, proli...
Dietary -linolenic acid inhibits proinflammatory cytokine production by peripheral blood mononuclear cells in hypercholesterolemic subjects1,2,3
Hypercholesterolemic subjects -linolenic acid eicosapentaenoic acid interleukin-6
2008/12/12
Background:Atherosclerosis is a chronic inflammatory disease. We previously reported that a diet high in -linolenic acid (ALA) reduces lipid and inflammatory cardiovascular disease risk factors in hyp...
α-Tocopherol modulates the low density lipoprotein receptor of human HepG2 cells
low density lipoprotein α-Tocopherol modulates
2008/4/23
The aim of this study was to determine the effects of vitamin E (α-tocopherol) on the low density lipoprotein (LDL) receptor, a cell surface protein which plays an important role in controlling blood ...
Low dose docosahexaenoic acid protects normal colonic epithelial cells from araC toxicity
colonic epithelial cells Low dose docosahexaenoic acid
2008/4/23
The nucleoside analogue arabinosylcytosine (araC) has been used for many years in the treatment of acute leukemia. Evidence in the literature suggests that araC may inhibit the growth of human colon c...
The effects of quercetin on SW480 human colon carcinoma cells: a proteomic study
human colon The effects of quercetin
2008/4/23
Background
High fruit and vegetable intake is known to reduce the risk of colon cancer. To improve understanding of this phenomenon the action of different phytochemicals on colon cells has been exam...
Different short- and long-term effects of resveratrol on nuclear factor-κB phosphorylation and nuclear appearance in human endothelial cells
atherosclerosis inflammatory disease red wine
2016/12/30
Resveratrol (a naturally occurring phytoalexin found in grapes and wine) has cardiovascular protective effects that suggest the antiatherogenic (ie, antiinflammatory) activities of the compound on end...
Is the fatty acid composition of immune cells the key to normal variations in human immune response?
normal variations human immune response
2016/12/30
Current interest in the effect of fats on human immune response is centered on the possibility that altering dietary intake could have a beneficial effect on a wide range of inflammatory and autoimmun...
Incorporation of docosahexaenoic acid into nerve membrane phospholipids: bridging the gap between animals and cultured cells
phosphatidylcholine brain retina
2017/1/4
Functional maturation of nervous tissues depends on membrane accretion of docosahexaenoic acid (DHA). Animal studies have shown that incorporation of dietary DHA into membrane phospholipids is dose de...
Relation between the fatty acid composition of peripheral blood mononuclear cells and measures of immune cell function in healthy, free-living subjects aged 25–72 y
Fatty acid immunity lymphocytes
2017/1/3
The objective of the study was to determine the relation between the fatty acid composition of human peripheral blood mononuclear cell (PBMC) phospholipids and the functions of human immune cells.