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A low-cost mechanical device for minimally invasive surgery
low-cost mechanical device minimally invasive surgery
2017/3/14
Surgeons can now use a new type of mechanical instrument to perform complex, minimally invasive procedures, also known as laparoscopic surgery, thanks to researchers and small business entrepreneurs f...
How Mechanical Force Triggers Blood Clotting at the Molecular Scale
Mechanical Forc Triggers Blood Clotting Molecular Scale
2016/8/23
Using a unique single-molecule force measurement tool, a research team has developed a clearer understanding of how platelets sense the mechanical forces they encounter during bleeding to initiate the...
Mechanical property and biocompatibility of PLLA coated DCPD composite scaffolds
biomedical engineering scaffolds biomaterial tissue engineering
2015/1/12
Dicalcium phosphate dihydrate (DCPD) cements have been used for bone repair due to its excellent biocompatibility and resorbability. However, DCPD cements are typically weak and brittle. To overcome t...
Signaling Pathways Involved in Mechanical Stimulation and ECM Geometry in Bone Cells
Mechanical Stimulation Osteoblast ECM
2015/1/12
The proliferation and differentiation of osteoblasts are influenced by mechanical and geometrical growth environments. A specific aim of my thesis was the elucidation of signaling pathways involved in...
Short-Term Exercise In Mice Increases Tibial Post-Yield Mechanical Properties While Two Weeks of Latency Following Exercise Increases Tissue-Level Strength
running mechanical properties histomorphometry extracellular matrix
2014/11/6
We have previously shown that exercise during growth increases post-yield deformation in C57BL6/129 (B6;129) male tibiae at the expense of reduced pre-yield deformation and structural and tissue stren...
Elevated Mechanical Loading When Young Provides Lifelong Benefits to Cortical Bone Properties in Female Rats Independent of a Surgically Induced Menopause
d mechanical loading exercise menopause bone properties
2014/11/6
Exercise that mechanically loads the skeleton is advocated when young to enhance lifelong bone health. Whether the skeletal benefits of elevated loading when young persist into adulthood and after men...
Applications of atomic force microscopy for the assessment of nanoscale morphological and mechanical properties of bone
Atomic Force Microscopy Scanning probe microscopy
2014/11/6
Scanning probe microscopy (SPM) has been in use for 30 years, and the form of SPM known as atomic force microscopy (AFM) has been around for 25 of those years. AFM has been used to produce high resolu...
In vivo reference point indentation reveals positive effects of raloxifene on mechanical properties following six months of treatment in skeletally mature beagle dogs
bone remodeling bone mechanics osteoporosis treatments indentation
2014/11/6
Raloxifene treatment has been shown previously to positively affect bone mechanical properties following one year of treatment in skeletally mature dogs. Reference point indentation (RPI) can be used ...
Nanoscale Changes in Collagen are Reflected in Physical and Mechanical Properties of Bone at the Microscale in Diabetic Rats
Zucker diabetic Sprague-Dawley Atomic Force Microscopy Raman Spectroscopy Reference Point Indentation D-spacing Advanced Glycation End Products
2014/11/6
Diabetes detrimentally affects the musculoskeletal system by stiffening the collagen matrix due to increased advanced glycation end products (AGEs). In this study, tibiae and tendon from Zucker diabet...
Cortical Bone Mechanical Properties Are Altered in an Animal Model of Progressive Chronic Kidney Disease
chronic kidney disease whole bone mechanical properties
2014/11/6
Chronic kidney disease (CKD), which leads tocortical bone loss and increasedporosity,increases therisk of fracture. Animal models have confirmed that these changes compromise whole bone mechanical pro...
Professor Peter T. C. So，The Department of Mechanical Engineering at Massachusetts Institute of Technology（图）
Professor Peter T. C. So The Department of Mechanical Engineering at Massachusetts Institute of Technology Measurement and Instrumentation Biomedical Engineering
2014/2/25
Peter T. C. So,Singapore Research Professor,Research Interests:Fluorescence microscopy and spectroscopy instrumentations, Deep tissue imaging, Functional imaging of cellular systems, Single Protein Dy...
Differential Response of Adult and Embryonic Mesenchymal Progenitor Cells to Mechanical Compression in Hydrogels
Embryonic stem cells Mesenchymal stem cells Hydrogel Biomechanics Chondrogenesis
2010/1/7
Cells in the musculoskeletal system can respond to mechanical
stimuli, supporting tissue homeostasis and remodeling.
Recent studies have suggested that mechanical stimulation
also influences the di...
Mechanical Strain-Stimulated Remodeling of Tissue-Engineered Blood Vessel Constructs
matrix metalloproteinase Tissue-Engineered Blood Vessel Constructs
2010/1/7
Progress in tissue-engineering research has renewed optimism about the possibility of constructing
a physiologically functional blood vessel substitute in the laboratory. To this end, we have explore...
A mechanical model for uterine muscle activity during labor and delivery
A mechanical model uterine muscle activity labor and delivery
2010/1/7
A mechanical model for uterine muscle activity during labor and delivery.
Dr.Caroline G.L.Cao,Associate Professor of The Department of Mechanical Engineeringat Tufts University（图）
Caroline G.L.Cao Associate Professor The Department of Mechanical Engineeringat Tufts University medical systems Mechanical Engineering
2010/1/6
Professor Cao’s research focus is in human factors of medical systems, including the design and evaluation of enabling technology (e.g., robotics, image guidance, haptics, training simulators) for min...