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The gastrointestinal HCO3- secretion functions to limit the mucosal acid damage due to HCl secreted in the stomach or organic acids produced in the large intestine. We studied HCO3- secretion in the...
Plasminogen activator (PA) is the enzyme that converts plasminogen to its active form, plasmin, which is involved in various physiological and pathological phenomena. The conversion is catalyzed by ...
Bicarbonate secretion occurs in almost all segments of the gastrointestinal tract. This study examined HCO3- secretion in the ileum, since it is less understood than HCO3- secretion in other intesti...
The exocyst is an octameric complex involved in docking or tethering of secretory vesicles to fusion sites of the plasma membrane. Sec6 is the core subunit of the exocyst complex. Here we identify an ...

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