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Explaining temporal trends in annualized relapse rates in placebo groups of randomized controlled trials in relapsing multiple sclerosis: systematic review and meta-regression
multiple sclerosis relapses annualized relapse rates placebo baseline characteristics eligibility criteria meta-analysis meta-regression systematic review
2013/4/27
Background: Recent studies have shown a decrease in annualised relapse rates (ARRs) in placebo groups of randomised controlled trials (RCTs) in relapsing multiple sclerosis (RMS).
Methods: We conduc...