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Multiple myeloma is an incurable bone marrow cancer that kills over 100,000 people every year. Known for its quick and deadly spread, this disease is one of the most challenging to address. As these c...
Researchers have developed a novel combination therapy using the anticancer agent mitoxantrone (MTX), together with an antibiotic, vancomycin, for treating bacteria that are resistant to the vancomyci...
近日,中南大学基础医学院 肿瘤研究所研究员陶永光团队与病理学系教授肖德胜团队在国际期刊Signal Transduction and Targeted Therapy(STTT, IF=38.104)发表了题为“GPR162 activates STING dependent DNA damage pathway as a novel tumor suppressor and radiation ...
What if, in people with blinding retinal disorders, one could simply introduce into the retina healthy photoreceptor cells derived in a dish from stem cells, and restore sight?
自2019年底以来,严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2)已经在全世界范围内引起了约5.3亿人感染,导致约1800万人死亡。几乎所有感染SARS-CoV-2的死亡患者都被发现是有细胞因子风暴综合症和病毒败血症,过度的炎症反应导致死亡率的增加,因此,防止过度炎症是避免细胞因子风暴综合症的关键。然而,目前,在临床或研究中应用的抗炎药物或免疫调节剂,包括针对炎症细胞因子(sarilu...
In the summer of 2010, Bill Ludwig and Doug Olson were battling an insidious blood cancer called chronic lymphocytic leukemia (CLL). They’d both received numerous treatments, and as remaining options ...
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer in humans. Some patients with NSCLC receive a therapy called immune checkpoint blockade (ICB) that helps kill cancer cells by ...
A Cornell-led research team’s improved cell therapy device effectively secreted insulin and controlled blood sugar in diabetic mice for up to six months – showing promise for the possibility of an eff...
近日,中南大学基础医学院、肿瘤研究所研究员陶永光团队在Signal Transduction and Targeted Therapy(IF=13.493)发表了题为“The Deubiquitylase UCHL3 Maintains Cancer Stem-Like Properties by Stabilizing the Aryl Hydrocarbon Receptor”的研究论文。中南...
Researchers at Duke University have discovered a way to enhance the effectiveness and safety of sonogenetics or ultrasonic modulation, emerging techniques that use sound waves to control the behavior ...
Individual tumors respond differently to cancer drugs, if at all. Until now, it remained a mystery why tumors have different reactions to the exact same therapy. But a new study at the USC Viterbi Sch...
Timothy Blake, a postdoctoral fellow in the Waymouth lab, was hard at work on a fantastical interdisciplinary experiment. He and his fellow researchers were refining compounds that would car...
Physicists at The University of Texas at Arlington have shown that using microwaves to activate photosensitive nanoparticles produces tissue-heating effects that ultimately lead to cell death within s...
An exhaustive analysis has been conducted of more than 12,000 distinct proteins present in an often aggressive and difficult to treat form of breast cancer, called triple-negative breast cancer.The re...
Small RNA molecules, including microRNAs (miRNAs) and small interfering RNAs (siRNAs), offer tremendous potential as new therapeutic agents to inhibit cancer-cell growth. However, delivering these sma...

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