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Exome Sequencing in an Admixed Isolated Population Indicates NFXL1 Variants Confer a Risk for Specific Language Impairment
Exome Sequencing Admixed Isolated Population NFXL1 Variants Specific Language Impairment
2015/5/13
Children affected by Specific Language Impairment (SLI) fail to acquire age appropriate language skills despite adequate intelligence and opportunity. SLI is highly heritable, but the understanding of...
Genome-wide analysis identifies a role for common copy number variants in specific language impairment
Genome-wide analysis copy number variants specific language impairment
2015/5/13
An exploratory genome-wide copy number variant (CNV) study was performed in 127 independent cases with specific language impairment (SLI), their first-degree relatives (385 individuals) and 269 popula...
Brain dynamics in the comprehension of action-related language. A time-frequency analysis of mu rhythms
Mu rhythms Beta rhythms Embodied meaning Action language Perceptive language
2015/5/13
EEG mu rhythms (8–13 Hz) recorded at fronto-central electrodes are generally considered as markers of motor cortical activity in humans, because they are modulated when participants perform an action,...
A de novo FOXP1 variant in a patient with autism, intellectual disability and severe speech and language impairment
FOXP1 variant autism intellectual disability severe speech language impairment
2015/5/13
FOXP1 (forkhead box protein P1) is a transcription factor involved in the development of several tissues, including the brain. An emerging phenotype of patients with protein-disrupting FOXP1 variants ...
Genome-wide association analyses of child genotype effects and parent-of-origin effects in specific language impairment
ALSPAC GWAS imprinting neurodevelopmental disorder specific language impairment
2015/5/5
Specific language impairment (SLI) is a neurodevelopmental disorder that affects linguistic abilities when development is otherwise normal. We report the results of a genome-wide association study of ...
Associations of HLA alleles with specific language impairment
Specific language impairment (SLI) HLA Neurodevelopmental disorders Genetic association
2015/5/5
Human leukocyte antigen (HLA) loci have been implicated in several neurodevelopmental disorders in which language is affected. However, to date, no studies have investigated the possible involvement o...
Odors are expressible in language, as long as you speak the right language
Olfaction Color Olfactory naming Cross-cultural Jahai Aslian
2015/5/5
From Plato to Pinker there has been the common belief that the experience of a smell is impossible to put into words. Decades of studies have confirmed this observation. But the studies to date have f...
Nodes and networks in the neural architecture for language: Broca’s region and beyond
Nodes networks neural architecture Broca’s region and beyond
2015/5/5
Current views on the neurobiological underpinnings oflanguage are discussed that deviate in a number of ways from the classical Wernicke–Lichtheim–Geschwind model. More areas than Broca’s and Wernicke...
Genome-wide screening for DNA variants associated with reading and language traits
pleiotropic variants CLDRC developmental dyslexia GWAS language meta-analysis reading reading disability SLIC specific language impairment
2015/5/5
Reading and language abilities are heritable traits that are likely to share some genetic influences with each other. To identify pleiotropic genetic variants affecting these traits, we first performe...
Homozygous microdeletion of exon 5 in ZNF277 in a girl with specific language impairment
ZNF277 SLI language
2015/5/5
Specific language impairment (SLI), an unexpected failure to develop appropriate language skills despite adequate non-verbal intelligence, is a heterogeneous multifactorial disorder with a complex gen...
AUTOMATIC SIGN LANGUAGE IDENTIFICATION
Sign language sign language identification language identification
2015/4/27
We propose a Random-Forest based sign language identification system. The system uses low-level visual features and is based on the hypothesis that sign languages have varying distributions of phoneme...
The Interplay of Genetic and Cultural Factors in Ongoing Language Evolution
Genetic Cultural Factors Language Evolution
2015/4/27
This chapter discusses recent advances in our understanding of the complex interplay between cultural and biological factors in language change and evolution. Three “myths” (the independence of biolog...
The Infrastructure of the Language-Ready Brain
The Infrastructure the Language-Ready Brain
2015/4/27
This chapter sketches in very general terms the cognitive architecture of both language comprehension and production, as well as the neurobiological infrastructure that makes the human brain ready for...
Genes: Interactions with Language on Three Levels—Inter-Individual Variation, Historical Correlations and Genetic Biasing
Interactions with Language Three Levels Inter-Individual Variation Historical Correlations Genetic Biasing
2015/4/27
The complex inter-relationships between genetics and linguistics encompass all four scales highlighted by the contributions to this book and, together with cultural transmission, the genetics of langu...
An amodal shared resource model of language-mediated visual attention
language vision computational modeling attention eye movements semantics
2015/4/27
Language-mediated visual attention describes the interaction of two fundamental components of the human cognitive system, language and vision. Within this paper we present an amodal shared resource mo...