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Annexin A2,A7,and A11 expression in head and neck squamous cell carcinoma
Annexin A2 annexin A7 annexin A11 squamous cell carcinoma head and neck neoplasms
2010/1/12
Aim: To investigate annexin A2 (ANXA2), annexin A7 (ANXA7), and annexin A11 (ANXA11) expression in head and neck squamous cell carcinoma (HNSCC). Although overexpression of ANXA2 has been reported in ...
Dendritic Cells—A Conductor of T Cell Differentiation—
dendritic cells regulatory T cells Th1 Th2 Th17
2010/11/18
Induction of different types of adaptive immune responses depending on the nature of antigens and the environmental context is crucial to cope with a variety of pathogens and concurrently to avoid pat...
Correlation between Grade in Transitional Cell Carcinoma (TCC) and Expression of Epidermal Growth Factor Receptor (EGFR)
Epidermal growth factor receptor (EGFR) Transitional Cell
2010/4/8
Background: The present study was undertaken to investigate the correlation of Epidermal Growth Factor Receptor (EGFR) expression with grade of Transitional Cell Carcinoma (TCC). Methods: Tumor sample...
Elimination of IL-13 Reverses Established Goblet Cell Metaplasia into Ciliated Epithelia in Airway Epithelial Cell Culture
anti-IL-13 antibody ciliated cells goblet cells IL-13 transition
2010/11/19
2 days after elimination of IL-13, the periodic acid-Schiff-positive area as well as MUC5AC protein level rapidly decreased. After 4 days, the number of goblet cells dramatically decreased, while that...
Antioxidant properties and prevention of cell cytotoxicity of Phlomis persica Boiss
Antioxidant activity DPPH scavenging β-Carotene bleaching test Cell cytotoxicity
2010/4/8
The free radical scavenging capacity, reducing power and inhibition of β–carotene peroxidation of Phlomis persica (PP) extracts was investigated. In addition, the effect of this extract on reduction o...
Adrenomedullin stimulates cyclic AMP production in the airway epithelial cells of guinea-pigs and in the human epithelial cell line
adrenomedullin airway cAMP epithelial cell guinea-pig human
2010/11/26
This study was designed to examine the effects of adrenomedullin (AM) on airway epithelial cells. Primary cultures of guinea-pig tracheal epithelial cells and the human bronchiolar epithelial cell lin...
Permeability of rat IgE across rat aortic endothelial cell is enhanced by histamine
IgE endothelial cells histamine permeability
2010/11/25
On the basis of results from the present study, histamine, acting via H2 receptors, enhances the permeability of rat IgE across the RAEC mono-layer. The increased permeability of endothelial cells ind...
Differences in mast cell-bound IgE in the nasal epithelial layer and lamina propria
allergic rhinitis IgE immunohistochemistry mast cell nasal mucosa
2010/11/25
Mast cells in the allergic nasal mucosa are reported to have higher concentrations of high affinity type I Fcε receptors (FcεRI) than mast cells in the non-allergic mucosa. IgE binds to FcεRI on mast ...
Mechanical strain-induced DNA synthesis and cell proliferation in human airway smooth muscle cells through extracellular signal-regulated kinase
airway smooth muscle cell extracellular signal-regulated kinase mechanical strain
2010/11/25
An increased airway muscle content is one of the characteristic features of airway remodeling. Proinflammatory substances, growth factors and mechanical strain promote airway muscle cell proliferation...
T cell signaling: Protein kinase Cθ, the immunological synapse and characterization of SLAT, a novel T helper 2-specific adapter protein
immune synapse protein kinase Cθ SLAT T cell receptor CD28 Th2
2010/11/24
Triggering of the antigen-specific T cell receptor (TCR) can lead to various functional outcomes, such as activation and proliferation, anergy or cell death. This differential signaling is mainly dete...
Pulmonary infiltration with eosinophilia syndrome complicated with non-Hodgkin's lymphoma of B cell lineage
bronchoalveolar lavage fluid interleukin-5 non-Hodgkin's lymphoma pulmonary infiltration with eosinophilia transbronchial lung biopsy
2010/11/24
Tissue eosinophilia is often seen in Hodgkin's disease and non-Hodgkin's lymphoma of T cell lineage. It is, however, rare in non-Hodgkin's lymphoma of B cell origin. We report a case of pulmonary infi...
Association of IgG Fc receptor II with tyrosine kinases in the human basophilic leukemia cell line KU812F
basophilic leukemia cell line IgG Fc receptor II intracellular calcium mobilization signal transduction tyrosine kinase
2010/11/24
The tyrosine kinase inhibitor genistein inhibited intracellular calcium mobilization caused by cross-linking of FcγRII in a dose-dependent manner. Rapid tyrosine phosphorylation after FcγRII cross-lin...
Effects of Th2 cytokines and eosinophils on stem cell factor production by lung fibroblasts
eosinophil fibroblast interleukin-4 interleukin-5 stem cell factor
2010/11/24
Interleukin-4 significantly enhanced SCF production, whereas tumor necrosis factor-α, interferon-γ and IL-1α showed suppressive effects on SCF pro-duction. When fibroblasts were cultured with IL-4 plu...
Inhibition of nasal mucosal eosinophils after immunotherapy is associated with a decrease in interleukin-13 mRNA and vascular cell adhesion molecule-1 expression
adhesion molecule allergic rhinitis apoptosis immunotherapy interleukin-13
2010/11/22
Analysis of the clinical data confirmed that the proportion of patients who showed greater than 60% improvement in symptoms (47 and 15%) and in rescue medication (79 and 10%) were significant for the ...
Human mast cell activation through Fc receptors and Toll-like receptors
adaptive immunity FcεRI FcγRI GeneChip innate immunity mast cell Toll-like receptor 4
2010/11/22
Mast cells express high-affinity IgE receptors (FcεRI) on their surface and can be activated to secrete a variety of biologically active mediators by cross-linking of receptor-bound IgE. Recent studie...