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Detectable Serum Severe Acute Respiratory Syndrome Coronavirus 2 Viral Load (RNAemia) Is Closely Correlated With Drastically Elevated Interleukin 6 Level in Critically Ill Patients With Coronavirus Disease 2019
coronavirus disease-19 (COVID-19) RNAemia IL-6 critically ill patients cytokine storm
2020/6/12
Although the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral load in respiratory specimens has been widely used to diagnose coronavirus disease 2019 (COVID-19), it is u...
Effectiveness of convalescent plasma therapy in severe COVID-19 patients
COVID-19 convalescent plasma treatment outcome pilot project
2020/6/12
Currently, there are no approved specific antiviral agents for novel coronavirus disease 2019 (COVID-19). In this study, 10 severe patients confirmed by real-time viral RNA test were enrolled prospect...
Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes
2019-nCoV Wuhan pneumonia epidemiology swabs intestine
2020/6/12
In December 2019, a novel coronavirus (2019-nCoV) caused an outbreak in Wuhan, China, and soon spread to other parts of the world. It was believed that 2019-nCoV was transmitted through respiratory tr...
Clinical Features and Treatment of 2019-nCov Pneumonia Patients in Wuhan: Report of A Couple Cases
Clinical Features Treatment 2019-nCov Pneumonia Patients Wuhan
2020/6/12
Till January 20, 2020, the 2019-new coronavirus (2019-nCoV) has caused more than one hundred cases in Wuhan (WMHC 2020). During a retrospective study of recent pneumonia patients in our department, we...
Comparing Teaching Methods on Skin Disorders Using Standardized Patients Dressed in Moulage vs Paper Cases
Comparing Teaching Methods
2018/11/22
Objective. To determine whether using standardized patients dressed in moulage improves pharmacy students’ ability to assess skin disorders compared to using picture-based paper cases. To determine ph...
Assessing Mental Health First Aid Skills Using Simulated Patients
Assessing Mental Simulated Patients
2018/11/21
Objective. To evaluate mental health first aid (MHFA) skills using simulated patients and to compare self-reported confidence in providing MHFA with performance during simulated patient roleplays.
Me...
Taurolidine-citrate-heparin lock reduces catheter-related bloodstream infections in intestinal failure patients dependent on home parenteral support: a randomized, placebo-controlled trial
antimicrobial catheter lock bacteremia catheter infections
2018/11/16
Background: In patients with intestinal failure who are receiving home parenteral support (HPS), catheter-related bloodstream infections (CRBSIs) inflict health impairment and high costs.
Folic acid therapy reduces serum uric acid in hypertensive patients: a substudy of the China Stroke Primary Prevention Trial (CSPPT)
controlled hyperuricemia olic acid supplementation new-onset hyperuricemia total homocysteine uric acid concentrations
2018/11/13
Background: The effect of folic acid supplementation on uric acid (UA) concentrations is still inconclusive.
Changes in skeletal muscle and organ size after a weight-loss intervention in overweight and obese type 2 diabetic patients
type 2 diabetes magnetic resonance imaging body composition skeletal muscle organ mass weight loss Look AHEAD trial
2018/11/12
Background: The effect of a weight-loss intervention on the masses of lean tissues and organs in humans is not well known.Objective: We studied the effects of a diet and exercise weight-loss intervent...
Prognostic relevance of prediagnostic weight loss and overweight at diagnosis in patients with colorectal cancer
colorectal neoplasms body composition body weight changes prognosis recurrence
2018/12/14
Background: Studies on the association between body mass index (BMI) and colorectal cancer (CRC) prognosis after diagnosis have yielded inconsistent results. Few studies have investigated associations...
Prognostic relevance of prediagnostic weight loss and overweight at diagnosis in patients with colorectal cancer
colorectal neoplasms body composition body weight changes prognosis recurrence
2018/12/18
Background: Studies on the association between body mass index (BMI) and colorectal cancer (CRC) prognosis after diagnosis have yielded inconsistent results. Few studies have investigated associations...
Factors correlated with hypermetabolism in patients with amyotrophic lateral sclerosis
ALS motor neuron disease leukocytosis
2016/6/14
Amyotrophic lateral sclerosis (ALS) is a severe
disease characterized by neurogenic amyotrophy and degeneration
of upper and lower motor neurons. Although ALS patients
usually experience reductions...
Similar metabolic responses to standardized total parenteral nutrition of septic and nonseptic critically ill patients
sepsis critically ill patients severity of illness
2016/6/14
Nutritional support is an important link between
the response to injury and recovery in critical illness.
Chronic administration of pharmacologic doses of vitamin E improves the cardiac autonomic nervous system in patients with type 2 diabetes
Vitamin E heart rate variability catecholamines
2016/6/13
Type 2 diabetes is associated with elevated oxidative
stress and declines in antioxidant defense. The disease is
also characterized by an imbalance in the ratio of cardiac sympathetic
to parasympat...
Amino acid kinetics in patients with sepsis
Sepsis hypermetabolism plasma amino acids amino acid elimination
2016/6/13
In patients with sepsis and systemic inflammatory
response syndrome, amino acid extraction by the liver is
enhanced, resulting in decreased plasma amino acid concentrations.
Systematic investigatio...