搜索结果: 1-12 共查到“知识库 Signal transduction”相关记录12条 . 查询时间(0.009 秒)
Signal Transduction and Targeted Therapy丨柳素玲团队等发现趋化因子CCL20通过重塑肿瘤免疫微环境促进乳腺癌进展的新机制（图）
乳腺癌 肿瘤干细胞 肿瘤恶性 生物医学研究院
2023/4/13
肿瘤微环境（tumor microenvironment，TME）在肿瘤恶性和治疗抵抗中发挥着重要作用。近年来，根据TME特点挖掘潜在靶点并开发安全有效的免疫疗法逐渐成为乳腺癌治疗的研究热点。2018年7月27日，复旦大学生物医学研究院/附属肿瘤医院柳素玲团队在PLOS Biology杂志在线发表了题为CCL20 triggered by chemotherapy hinders the ther...
周玉峰团队在《Signal Transduction and Targeted Therapy》上发表Covid-19感染的细胞因子风暴信号通路和治疗的长篇综述（图）
COVID-19 周玉峰团队 细胞因子 免疫球蛋白 糖皮质激素
2023/4/17
2021年7月7日，复旦大学生物医学研究院/附属儿科医院周玉峰研究员与英国格拉斯哥大学/深圳大学医学院徐大模教授合作在Signal Transduction and Targeted Therapy杂志上发表了一篇题为The signal pathways and treatment of cytokine storm in COVID-19 的长篇综述。
National Institutes of Health workshop: Role of Nutrient Regulation of Signal Transduction in Metabolic Diseases
Signal Transduction Metabolic Diseases
2016/6/1
Nutritive and nonnutritive dietary constituents can promote or
hinder the development of several chronic diseases, including
cancer, obesity, inflammatory diseases, diabetes, and cardiovascular
dis...
Characterization of arachidonic acid -mediated signal transduction in regulation of NIH -3T3 cell adhesion to extracellular matrix
Matrix the discrete form cells cell proliferation lipid protein cell fibronectin
2014/12/11
Cell-extracellular matrix (ECM) adhesion is characterized by discrete morphological and functional stages beginning with cell-substrate attachment, followed by cell spreading and then migration. These...
Mathematical model for positive feedback and temperature induced signal transduction and differential gene regulation in {\it Bordetella pertussis}}
Mathematical model positive feedback temperature induced signal
2011/9/9
Based on the phosphorelay kinetics operative within BvgAS two component system we propose a mathematical model for signal transduction and differential gene regulation in Bordetella pertussis. To unde...
Towards Biochemical Filter with Sigmoidal Response to pH Changes: Buffered Biocatalytic Signal Transduction
Towards Biochemical Sigmoidal Response Buffered Biocatalytic Signal Transduction
2010/11/22
We realize a biochemical filtering process based on the introduction of a small quantity
of a buffer in a biocatalytic signal-transduction logic system based on the function of an
enzyme, esterase. ...
Sensitivity analysis of a computational model of the IKK-NF-κB-IκBα-A20 signal transduction network
Sensitivity analysis computational model IKK-NF-κB-IκBα-A20 signal transduction
2010/11/15
The NF-{\kappa}B signaling network plays an important role in many different compartments of the immune system during immune activation. Using a computational model of the NF-{\kappa}B signaling netw...
Kaempferol,a Tea Flavonol,Effect on Interleukin-2 Signal Transduction of Human T Cell Leukemia
cytokine tea (Camellia sinensis L.) NFAT (nuclear factor expression ofactivated T cell)
2009/9/9
CCRF-CEM and Jurkat E6-1, human T cell leukemia, produced interleukin (IL)-2 stimulated with
phorbol myristate acetate (PMA) and pokeweed mitogen (PWM). IL-2 cytokine production and
mRNA expression ...
Effect of TGF-β1 stimulation on the Smad signal transduction pathway of human peritoneal mesothelial cells
mesothelial cells TGF-β1 Smad2/3 Smad7 extracellular matrix
2009/4/9
Objective: To prove whether the SMAD signal transduction pathway in human peritoneal mesothelial cells (HPMCs) influenced the process of human peritoneal fibrosis stimulated by TGF-β1.Methods HPMCs we...
Pyrrolnitrin Interferes with Osmotic Signal Transduction in Neurospora crassa
dicarboximide glycerol two-component signal transduction biocontrol histidine kinase respiration
2009/3/5
Pyrrolnitrin, produced by several bacteria that are used in biological control, has an inhibitory effect on the electron transport system of respiration in Neurospora crassa. We have previously desc...
Signal transduction by FcεRI: Analysis of the early molecular events
IgE receptor mast cells membrane receptors tyrosine phosphorylation
2010/11/29
We are analysing the initial molecular events stimulated by the high-affinity receptor for IgE, FcεRI. Earlier studies have shown that the first response when the receptor-bound IgE interacts with a m...
Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation
Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated Stress Inflammation
2014/3/31
Mitogen-activated protein kinase (MAPK) signal transduction pathways are among the most widespread mechanisms of eukaryotic cell regulation. All eukaryotic cells possess multiple MAPK pathways, each o...