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Background: A high dietary calcium intake with adequate vitamin D status has been linked to lower colorectal cancer risk, but the mechanisms of these effects are poorly understood.
Background: Tuberculosis (TB) is a major global health problem, which has been ranked as the second leading cause of death from an infectious disease worldwide. Diagnosis based on cultured specimens i...
Primary immunodeficiency (PID) is an intrinsic defect of the immune system. Patients with PID have increased susceptibility to recurrent and persistent infections, but other symptoms are also common.
Chemotaxis is defined as the unidirectional movement of a cell in response to a chemical gradient in the direction from a low to a high concentration of chemoattractant.
A variety of cell types are important components of the immune system. They constitute some of the body’s main defences against infection.
The innate immune system contains a range of cell-bound and soluble proteins which eliminate pathogens by recognizing unique molecular patterns expressed by microorganisms, but not by host cells. Alte...
The susceptibility of various strains of mice to infection by Leishmania tropica (major) was recently studied in this laboratory. The infection in A/J, C3H, CBA, AKR/J, AKR/CU, and C57B1 mice (the sem...
A serum survey was conducted to determine the immune status of children 2 months to 6 Years old to polio virus type I, II and III related to the history of oral polio vaccination in Fashapouye (A rura...
Background: Crystalline silica may act as an immune adjuvant to increase inflammation and antibody production. The high­est exposures to silica are known to occur in the dusty trades industries su...
The aim of this study was to investigate the systemic humoral and cell-mediated immune system parameters, and glial fibrillary acidic protein (GFAP) immunoreactivity in non-convulsive absence epilepsy...
Immunomodulators such as lipopolysaccharides (LPS) and forskolin change the nature of dendritic cells (DCs) to induce Th1 and Th2 cells, respectively, thereby designated Th1 or Th2 adjuvants. Recent s...
Syphilis is a well-known sexually transmitted disease found around the world. Malaria and syphilis are endemic in many regions of the world, and co-infection with the two pathogens is common. Here, th...
After taking up pathogen-derived antigens, dendritic cells (DCs) leave peripheral organs and migrate into sentinel lymph nodes via afferent lymphatic vessels. During this process, they undergo maturat...
In the last decade several teams of researchers obtained in vitro drug-specific human T-cell clones, in a variety of clinical types of drug eruptions. These clones were produced from blood or skin mon...
Drug-induced hypersensitivity reactions have been explained by the hapten concept, according to which a small chemical compound is too small to be recognized by the immune system. Only after covalentl...

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