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Cold Agglutinin Disease; A Laboratory Challenge
Cold Agglutinin Disease Hemolytic Anemia Sysmex Autoanalyzer
2015/11/9
Introduction: Autoimmune haemolytic anemia (AIHA) is a complex process characterized by an immune reaction against red blood cell self-antigens. The analysis of specimens, drawn from patients with col...
A Fifty-year challenge in managing drug addiction in Malaysia
Fifty-year challenge drug addiction Malaysia
2015/7/28
The history of substance abuse in Malaysia can be divided into pre- and post-independent era. In pre-independence, the main drug of abuse was opium which was initially consumed by immigrants from Chin...
Lateral Traumatic Esophago-Cutaneous fistula in a Child; Platelet-Rich Fibrin Glue Challenge
Fistula Wounds and Injuries
2015/9/30
Introduction: The endoscopic fibrin glue or platelet-rich fibrin glue (PRFG) injection is an easy, safe and effective technique for the fistula. So far, the use of fibrin glue has been limited to sele...
Diagnosis of Food Allergy Based on Oral Food Challenge Test
food hypersensitivity guideline immunoglobulin E oral food challenge tolerance
2010/11/16
Diagnosis of food allergy should be based on the observation of allergic symptoms after intake of the suspected food. The oral food challenge test (OFC) is the most reliable clinical procedure for dia...
The annual incidence of traumatic spinal cord injury (SCI) in developed countries varies between 11.5-53.4 per million population. [1] Cervical spine trauma accounts for 55% of all spinal cord injurie...
Efficacy of Levocabastine Hydrochloride Ophthalmic Suspension in the Conjunctival Allergen Challenge Test in Japanese Subjects with Seasonal Allergic Conjunctivitis
allergen challenge test allergic conjunctivitis conjunctival itching levocabastine hydrochloride redness
2010/11/18
The mean itching score in the levocabastine-treated group was 0.08 ± 0.06, which was significantly lower than the mean score of 1.98 ± 0.16 in the vehicle group (P < 0.0001). The redness and chemosis...
Exercise challenge in patients with asthma whose peak expiratory flow values are controlled within the green zone
airway hyperreactivity exercise-induced asthma green zone peak expiratory flow
2010/11/29
Recent guidelines for the management of asthma recommend that peak expiratory flow (PEF) should be measured to monitor the level of airflow limitation and to maintain PEF values within the green zone ...
Methacholine, cold air and exercise challenge tests in the diagnosis of bronchial responsiveness at school age: A follow-up study from birth to school age
bronchial responsiveness cold air exercise test intrauterine growth retardation methacholine
2010/11/24
Bronchial hyperresponsiveness was common (up to 62%) at school age in children born as moderately preterm. The outdoor exercise bronchodilation test found 61% of all BHR cases. Bronchial hyperresponsi...
Repeated antigen challenge in patients with perennial allergic rhinitis to house dust mites
nasal provocation test perennial allergic rhinitis priming effect repeated antigen challenge
2010/11/24
In contrast with pollinosis, nasal provocation reactions were not clearly enhanced by repeated provocation. To further understand nasal reactions induced by antigen challenge, studies should be perfor...
Reproducibility of nasal function measurements with histamine and adenosine monophosphate nasal challenge testing in patients with allergic rhinitis
adenosine monophosphate allergic rhinitis histamine nasal challenge nasal inspiratory flow
2010/11/24
Baseline CV prior to histamine were 15.1, 19.6 and 15.8 for PIFR, AR and Rhino, respectively; prior to AMP, baseline CV were 12.7, 19.6 and 10.6% for PIFR, AR and Rhino, respectively. For histamine ch...
Time-course changes in nasal airway resistance after house dust antigen challenge: With special reference to late phase response
antigen challenge basophilic cells eosinophil house dust mite late phase response nasal airway resistance perennial nasal allergy
2010/11/29
The definition of late-phase response (LPR) associated with nasal allergy is not as clear as that associated with asthma. Furthermore, LPR and immediate-phase response often act in concert to produce ...
Effect of a thromboxane A2 receptor antagonist, ramatroban (BAY u 3405), on inflammatory cells, chemical mediators and non-specific nasal hyperreactivity after allergen challenge in patients with perennial allergic rhinitis
eosinophil nasal allergen challenge nasal mucosal reactivity perennial allergic rhinitis ramatroban thromboxane A2 receptor antagonist
2010/11/29
In some clinical studies performed in patients with perennial allergic rhinitis, ramatroban, a new thromboxane A2 receptor antagonist, significantly improved nasal symptoms. As yet the mechanism of ac...