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In vitro production of a TRH-homologous peptide and His-Pro diketopiperazine by human semen
TRH-like peptide His-Pro diketopiperazine peptide biosynthesis in semen
2009/2/23
Fresh human semen, diluted 1:1 v/v with 0.15 M NaCl- 0.05 M phosphate, pH 7.5, undergoes a 3-fold increase in total thyrotropin-releasing hormone (TRH) immunoreactivity on incubation at 4 C for 8 to...
Human semen contains thyrotropin releasing hormone（TRH）, a TRH-homologous peptide, and TRH-binding substances
semen TRH vasectomy exclusion ion exchange high pressure chromatography
2009/2/20
High levels of thyrotropin releasing hormone (TRH) and TRH-homologous peptide, with the general structure pGlu=X-Pro-NH2 where X is either Histidine (His) or a neutral amino acid residue, have been ...
Increased in vitro binding of fresh and frozen-thawed human sperm exposed to a synthetic peptide
Profertility peptide sperm-egg binding human
2009/2/18
Prosaposin is a well-characterized, approximately 68-kDa protein found in many tissues and as a normal component of human semen. A fragment of prosaposin apparently is involved in primary sperm-eg...
Exposure of thawed frozen bull sperm to a synthetic peptide before artificial insemination increases fertility
Enhancement of fertility bovine sperm prosaposin
2009/2/18
We evaluated the effect on fertility of in vitro exposure of thawed frozen bull sperm to synthetic FertPlus peptide prior to artificial insemination (AI). The peptide represented a 60-amino acid s...
Exposure of human, boar, or bull sperm to a synthetic peptide increases binding to an egg-membrane substrate
human boar bull sperm synthetic peptide increases egg-membrane substrate
2009/2/18
We evaluated the effects of in vitro exposure of sperm to synthetic FertPlus peptide, which represents a 60-amino acid sequence within rat prosaposin, using a microwell sperm-binding assay (SBA), ...
The effects of antifreeze peptide III (AFP) and insulin transferrin selenium（ITS）on cryopreservation of chimpanzee（Pan troglodytes）spermatozoa
Semen acrosome CAMA FITC-PSA
2009/2/17
We investigated the effects of antifreeze peptides (AFP) and insulin transferrin selenium (ITS) on the motility and membrane integrity of chimpanzee (Pan troglodytes) spermatozoa after chilling (0...
Comparison of responses to adrenomedullin and calcitonin gene-related peptide in the feline erection model
ADM CGRP penile erection nitric oxide KATp channe
2009/2/17
The purpose of the present study was to investigate the effects of intracavernosal injections of adrenomedullin (ADM) and calcitonin gene-related peptide (CGRP), two structurally similar peptides,...
Localization and effects of calcitonin gene-related peptide in the testicular vasculature of the rat
CGRP testis blood flow vasomotion
2009/2/17
Using laser Doppler flowmetry, the effects of unilateral intratesticular injection of calcitonin gene-related peptide (CGRP) and CGRP8-37, a CGRP-receptor antagonist, on right- and left-testicular b...
Sperm immobilizing activity of a synthetic bioactive peptide 20-44 of 37-kDa cationic antimicrobial protein（CAP37）of human neutrophils
Amphipathic peptides antisperm antibodles complement neutrophil granule-associated protein
2009/2/13
We have previously reported that human sperm coincubated with human peripheral blood neutrophils in the presence of complement (C)-fixing antisperm antibody (ASA)-positive sera are rapidly interna...
Human chorionic gonadotropin but not the calcitonin gene-related peptide induces postnatal testicular descent in mice
Cryptorchidism mechanisms androgens paracnne factors gonadotropins testes
2009/2/13
The androgen-regulated paracrine factor, calcitonin gene-related peptide (CGRP), has been proposed as a possible mediator of testicular descent. This peptide has been found to increase rhythmic co...
Involvement of vasoactive intestinal peptide（VIP）as a humoral mediator of penile erectile function in the dog
vasoactive intestinal peptide（VIP） humoral mediator penile erectile function dog
2009/2/12
The effects of intracorporeal infusion of anti-vasoactive intestinal peptide (anti-VIP) antisera on electrically induced penile erection were studied in 18 male mongrel dogs. Electrical pulse stimul...
Atrial natriuretic peptide（ANP）as a stimulus of the human acrosome reaction and a component of ovarian follicular fluid：correlation of follicular ANP content with in vitro fertilization outcome
Noncapacitated spermatozoa capacitation
2009/2/12
Atrial natriuretic peptides (ANPs) from several species induced the human acrosome reaction. The maximal response was highest for human ANP (18.6% above unstimulated or baseline values) and decrea...
Atrial natriuretic peptide precursor material in rat testis
ANP mRNA RF-HPLC northern blot hybridization
2009/2/6
Atrial natriuretic peptide (ANP) has recently been suggested to play a role in the regulation of male reproduction. Specifically, it has been shown to affect steroidogenesis in Leydig cells. The dat...
Immunobiology of a synthetic luteinizing hormone receptor peptide 21-41
Testicular function spermatogenesis receptor antibodies
2008/12/29
Immunization of adult male rabbits with a synthetic luteinizing hormone-receptor peptide (LH-RP; representing amino-acids 21-41 of the extracellular domain of the rat LH receptor) resulted in prod...
Chronic Administration of Atrial Natriuretic Peptide Reduces Testosterone Production of Testes in Mice
ANP spermatogenesis testosterone
2008/12/19
The purpose of the present study was to examine the effect of the long-term administration of human atrial natriuretic peptide (ANP) on testosterone production in male mice. Twenty-five mice recei...